Simulation of Cumulative Exposure Statistics for Blast Pressure Transmission Into the Brain.
Introduction: This study develops and demonstrates an analysis approach to understand the statistics of cumulative pressure exposure of the brain to repetitive blasts events.Materials and Methods: A finite element model of blast loading on the head was used for brain model biomechanical responses. T...
| Publicado en: | Military Medicine Vol. 185; pp. 214 - 227 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Oxford University Press / USA
2020 Supplement
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141923105&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141923105 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00264075 4DV jtl: Military Medicine issn: 00264075 maglogo: N pubinfo: dt: 2020 Supplement vid: 185 pid: 622 pub: Oxford University Press / USA artinfo: ui: 141923105 141923105 NLM32074364 141923105 10.1093/milmed/usz308 NLM32074364 141923105 ppf: 214 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Simulation of Cumulative Exposure Statistics for Blast Pressure Transmission Into the Brain. aug: au: Tan, X Gary Matic, Peter affil: Materials Science and Technology Division (Code 6300), U.S. Naval Research Laboratory, 4555 Overlook Ave SW, Washington, DC 20375 sug: subj: Disasters Classification Blast Injuries Complications Brain Physiology Human Finite Element Analysis Systems Analysis Brain Physiopathology Kinematics Physiology Pressure Adverse Effects Blast Injuries Physiopathology Validation Studies Comparative Studies Evaluation Research Multicenter Studies ab: Introduction: This study develops and demonstrates an analysis approach to understand the statistics of cumulative pressure exposure of the brain to repetitive blasts events.Materials and Methods: A finite element model of blast loading on the head was used for brain model biomechanical responses. The cumulative pressure exposure fraction (CPEF), ranging from 0.0 to 1.0, was used to characterize the extent and repetition of high pressures. Monte Carlo simulations were performed to generate repetitive blast cumulative exposures.Results: The blast orientation effect is as influential as the blast overpressure magnitudes. A 75° (from the side) blast orientation can produce CPEF values exceeding traumatic brain injury pressure thresholds >0.95 while, for the same blast overpressure, a 0° (front) blast orientation results in a CPEF <0.25. Monte Carlo results for different sequences reflecting notional operational and training environments show that both mean values and standard deviations of CPEF reach the statistically equilibrium state at a finite value of n exposures for each sequence.Conclusions: Statistical convergence of the brain pressure response metrics versus number of blasts for different exposures characterizes the transitions from "low" to "high" number of blasts and quantitatively highlights the differences between operational and training exposures. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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