A Survey of Academic Intensivists' Use of Neuromuscular Blockade in Subjects With ARDS.
BACKGROUND: Our Cooling to Help Injured Lungs (CHILL) trial of therapeutic hypothermia in ARDS includes neuromuscular blockade (NMB) as an inclusion criterion to avoid shivering. NMB has been used to facilitate mechanical ventilation in ARDS and was shown to reduce mortality in the ACURASYS trial. T...
| Publicado en: | Respiratory Care Vol. 65; no. 3; pp. 362 - 369 |
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| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Mar2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=141940024&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 141940024 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Mar2020 vid: 65 iid: 3 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 141940024 141940024 141940024 10.4187/respcare.07026 141940024 ppf: 362 ppct: 7 formats: fmt: @attributes: type: P tig: atl: A Survey of Academic Intensivists' Use of Neuromuscular Blockade in Subjects With ARDS. aug: au: Dodia, Neal N. Richert, Mary E. Deitchman, Andrew R. Quinn, Charlene C. Marciniak, Ellen T. Brown, Clayton H. Terrin, Michael L. Amariei, Diana E. Shanholtz, Carl B. Hasday, Jeffrey D. affil: Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland sug: subj: Critical Care Physician Attitudes Respiratory Distress Syndrome, Acute Drug Therapy Neuromuscular Blockade Utilization Neuromuscular Blocking Agents Administration and Dosage Decision Making, Clinical Academic Medical Centers Human Cross Sectional Studies Questionnaires United States Ventilators, Mechanical Neuromuscular Blocking Agents Therapeutic Use Descriptive Statistics Chi Square Test ab: BACKGROUND: Our Cooling to Help Injured Lungs (CHILL) trial of therapeutic hypothermia in ARDS includes neuromuscular blockade (NMB) as an inclusion criterion to avoid shivering. NMB has been used to facilitate mechanical ventilation in ARDS and was shown to reduce mortality in the ACURASYS trial. To assess the feasibility of a multi-center CHILL trial, we conducted a survey of academic intensivists about their NMB use in patients with ARDS. METHODS: We distributed via email a 16-question survey about NMB use in patients with ARDS including frequency, indications, and dosing strategy. RESULTS: 212 (24.3%) of 871 respondents completed the survey: 94.7% were board-certified in internal medicine, 88% in pulmonary and critical care; 90.3% practiced in academic medical centers, with 87% working in medical ICUs; 96.6% of respondents who treat ARDS use NMB, and 39.7% use NMB in ≥ 50% of these patients. Of 4 listed indications for initiating NMB in ARDS, allowing adherence with lung-protective ventilator strategies and patient--ventilator synchrony were cited as the most important reasons, followed by the results of the ACURASYS trial and facilitating prone positioning. CONCLUSIONS: We conclude that NMB is frequently used by academic intensivists to facilitate mechanical ventilation in patients with moderate to severe ARDS. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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