Neuronavigated 1 Hz rTMS of the left angular gyrus combined with visuospatial therapy in post-stroke neglect.

BACKGROUND: Visuospatial neglect (VSN) may be caused by an inter-hemispheric imbalance of neural activity after brain injury. Repetitive transcranial magnetic stimulation (rTMS) allows rebalancing restoration to a certain degree, relieving neglect symptoms. OBJECTIVE: This study investigates the the...

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Published in:NeuroRehabilitation Vol. 46; no. 1; pp. 83 - 94
Main Authors: Iwański, Szczepan, Leśniak, Marcin, Polanowska, Katarzyna, Bembenek, Jan, Czepiel, Wojciech, Seniów, Joanna
Format: research tables/charts randomized controlled trial Journal Article
Published: Sage Publications Inc. 2020
Online Access:View this record in EBSCOhost
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      dt: 2020
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        10.3233/NRE-192951
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        atl: Neuronavigated 1 Hz rTMS of the left angular gyrus combined with visuospatial therapy in post-stroke neglect.
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          Iwański, Szczepan
          Leśniak, Marcin
          Polanowska, Katarzyna
          Bembenek, Jan
          Czepiel, Wojciech
          Seniów, Joanna
        affil: 2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland
      sug:
        subj:
          Stroke Rehabilitation
          Perceptual Disorders Therapy
          Transcranial Magnetic Stimulation Methods
          Parietal Lobe Physiopathology
          Human
          Female
          Male
          Middle Age
          Aged
          Randomized Controlled Trials
          Random Assignment
          Control Group
          Treatment Duration
          Time Factors
          Psychological Tests
          Outcome Assessment
          Descriptive Statistics
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
          Male
      ab: BACKGROUND: Visuospatial neglect (VSN) may be caused by an inter-hemispheric imbalance of neural activity after brain injury. Repetitive transcranial magnetic stimulation (rTMS) allows rebalancing restoration to a certain degree, relieving neglect symptoms. OBJECTIVE: This study investigates the therapeutic effect of 1 Hz rTMS applied over the left angular gyrus combined with visual scanning training in patients with left VSN in the subacute stroke phase. METHODS: Twenty-eight patients with VSN were randomly assigned to either experimental (fifteen sessions of rTMS consisted of 1800 magnetic pulses delivered to the left angular gyrus with a neuronavigation control), or control group (fifteen sessions of sham stimulation), followed by visual scanning training. VSN severity was assessed both before and after treatment with a 3-month follow up employing the Behavioural Inattention Test and functional measures. RESULTS: No statistically significant differences were detected in outcome measures between the rTMS and sham groups after completion of 3-week therapy and at 3-month follow up. The magnitude of stimulation effects was not associated either with lesion volume, its location, or baseline motor threshold. CONCLUSIONS: Our study did not confirm efficacy of 1 Hz rTMS over the angular gyrus as an adjuvant method to visual scanning training in patients with VSN in the subacute stroke.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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