Real-Time Detection of Hemothorax and Monitoring its Progression in a Piglet Model by Electrical Impedance Tomography: A Feasibility Study.

Hemothorax is a serious medical condition that can be life-threatening if left untreated. Early diagnosis and timely treatment are of great importance to produce favorable outcome. Although currently available diagnostic techniques, e.g., chest radiography, ultrasonography, and CT, can accurately de...

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Publicado en:BioMed Research International pp. 1 - 14
Autores principales: Yang, Lin, Zhang, Chao, Liu, Wenbo, Wang, Hang, Xia, Junying, Liu, Benyuan, Shi, Xuetao, Dong, Xiuzhen, Fu, Feng, Dai, Meng
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2/28/2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/1357160
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        atl: Real-Time Detection of Hemothorax and Monitoring its Progression in a Piglet Model by Electrical Impedance Tomography: A Feasibility Study.
      aug:
        au:
          Yang, Lin
          Zhang, Chao
          Liu, Wenbo
          Wang, Hang
          Xia, Junying
          Liu, Benyuan
          Shi, Xuetao
          Dong, Xiuzhen
          Fu, Feng
          Dai, Meng
        affil: Department of Aerospace Medicine, Fourth Military Medical University, Xi'an, China
      sug:
        subj:
          Hemothorax Diagnosis
          Disease Progression
          Electric Impedance Methods
          Tomography Methods
          Animal Studies
          Swine
          Injections
          Blood Transfusion, Autologous
          Early Diagnosis
          Hemothorax Therapy
      ab: Hemothorax is a serious medical condition that can be life-threatening if left untreated. Early diagnosis and timely treatment are of great importance to produce favorable outcome. Although currently available diagnostic techniques, e.g., chest radiography, ultrasonography, and CT, can accurately detect hemothorax, delayed hemothorax cannot be identified early because these examinations are often performed on patients until noticeable symptoms manifest. Therefore, for early detection of delayed hemothorax, real-time monitoring by means of a portable and noninvasive imaging technique is needed. In this study, we employed electrical impedance tomography (EIT) to detect the onset of hemothorax in real time on eight piglet hemothorax models. The models were established by injection of 60 ml fresh autologous blood into the pleural cavity, and the subsequent development of hemothorax was monitored continuously. The results showed that EIT was able to sensitively detect hemothorax as small as 10 ml in volume, as well as its location. Also, the development of hemothorax over a range of 10 ml up to 60 ml was well monitored in real time, with a favorable linear relationship between the impedance change in EIT images and the volume of blood injected. These findings demonstrated that EIT has a unique potential for early diagnosis and continuous monitoring of hemothorax in clinical practice, providing medical staff valuable information for prompt identification and treatment of delayed hemothorax.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
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      ougenre: Article
    language: English
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