Sociodemographic and Lifestyle Factors in Relation to Gastric Cancer in a High-Risk Region of China: A Matched Case–Control Study.

Objectives: To explore the role of sociodemographic and lifestyle factors in the development of gastric cancer in a high-risk region of China. Methods: In a case–control study, all newly diagnosed patients with gastric cancer were compared with healthy controls matched (1:1) by sex, age (±3 years),...

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Publicado en:Nutrition & Cancer Vol. 72; no. 3; pp. 421 - 431
Autores principales: Lin, Yulan, Wu, Chuancheng, Yan, Wei, Guo, Saixiong, Lin, Su, Liu, Baoying
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2020
Acceso en línea:Ver este registro en EBSCOhost
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        10.1080/01635581.2019.1638425
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        atl: Sociodemographic and Lifestyle Factors in Relation to Gastric Cancer in a High-Risk Region of China: A Matched Case–Control Study.
      aug:
        au:
          Lin, Yulan
          Wu, Chuancheng
          Yan, Wei
          Guo, Saixiong
          Lin, Su
          Liu, Baoying
        affil: Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University, Fuzhou, China
      sug:
        subj:
          Life Style
          Socioeconomic Factors
          Stomach Neoplasms Risk Factors
          China
          Case Control Studies
          Family Characteristics
          Helicobacter Infections
          Odds Ratio
          Confidence Intervals
          Family History
          Smoking
          Tea Utilization
          Refrigeration Utilization
      ab: Objectives: To explore the role of sociodemographic and lifestyle factors in the development of gastric cancer in a high-risk region of China. Methods: In a case–control study, all newly diagnosed patients with gastric cancer were compared with healthy controls matched (1:1) by sex, age (±3 years), and place of residence during 2013–2017. Results: A total of 622 gastric cancer and 622 healthy controls were included. Larger household size (>4 family members) appeared to decrease gastric cancer risk for Helicobacter pylori-negative ones (odd ratio = 0.43, 95% CI = 0.26–0.70). Similarly, longer refrigerator ownership was associated with a 67% decreased risk in H. pylori-negative group (95% CI = 0.15–0.77). Participants with a family history of gastric cancer had nearly fivefold higher risk (odd ratio = 4.88, 95% CI = 2.49–9.55). Smoking attributed to 83% increased risk (odd ratio = 1.83, 95% CI = 1.19–2.80). Tea consumption dramatically decreased risk in whole study population (odd ratio = 0.28, 95% CI = 0.17–0.45). Conclusions: In summary, family history, smoking, H. pylori-related chronic atrophic gastritis, and H. pylori infection were positively associated with gastric cancer. Whereas, tea consumption and refrigerator use negatively associated with gastric cancer and could be promoted to reduce gastric cancer rate in high-risk populations, especially in the developing regions.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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