Diagnostic performance and inter-operator variability of apparent diffusion coefficient analysis for differentiating pleomorphic adenoma and carcinoma ex pleomorphic adenoma: comparing one-point measurement and whole-tumor measurement including radiomics approach.
Background and Purpose: The purpose of this study was to compare the diagnostic performance between apparent diffusion coefficient (ADC) analysis of one-point measurement and whole-tumor measurement, including radiomics for differentiating pleomorphic adenoma (PA) from carcinoma ex pleomorphic adeno...
| Published in: | Japanese Journal of Radiology Vol. 38; no. 3; pp. 207 - 215 |
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| Main Authors: | , , , , , , |
| Format: | research Journal Article |
| Published: |
Springer Nature
Mar2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142128912&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142128912 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Mar2020 vid: 38 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 142128912 142128912 NLM31820265 142128912 10.1007/s11604-019-00908-1 NLM31820265 142128912 ppf: 207 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Diagnostic performance and inter-operator variability of apparent diffusion coefficient analysis for differentiating pleomorphic adenoma and carcinoma ex pleomorphic adenoma: comparing one-point measurement and whole-tumor measurement including radiomics approach. aug: au: Wada, Takeshi Yokota, Hajime Horikoshi, Takuro Starkey, Jay Hattori, Shinya Hashiba, Jun Uno, Takashi affil: Department of Radiology, Chiba University Hospital, 1-8-1, Inohana Chuo-ku, 260-8677, Chiba, Japan sug: subj: Image Interpretation, Computer Assisted Methods Salivary Gland Neoplasms Clinical Competence Statistics and Numerical Data Adenoma Male Pharmacokinetics Middle Age Observer Bias Female Human Reproducibility of Results Salivary Glands Diagnosis, Differential Magnetic Resonance Imaging ROC Curve Algorithms Validation Studies Comparative Studies Evaluation Research Multicenter Studies Impact of Events Scale Middle Aged: 45-64 years Male Female ab: Background and Purpose: The purpose of this study was to compare the diagnostic performance between apparent diffusion coefficient (ADC) analysis of one-point measurement and whole-tumor measurement, including radiomics for differentiating pleomorphic adenoma (PA) from carcinoma ex pleomorphic adenoma (CXPA), and to evaluate the impact of inter-operator segmentation variability.Materials and Methods: One hundred and fifteen patients with PA and 22 with CXPA were included. Four radiologists with different experience independently placed one-point and whole-tumor ROIs and a radiomics-predictive model was constructed from the extracted imaging features. We calculated the area under the receiver-operator characteristic curve (AUC) for the diagnostic performance of imaging features and the radiomics-predictive model.Results: AUCs of the imaging features from whole-tumor varied between readers (0.50-0.89). The most experienced radiologist (Reader 1) produced significantly high AUCs than less experienced radiologists (Reader 3 and 4; P = 0.01 and 0.009). AUCs were higher for the radiomics-predictive model (0.82-0.87) than for one-point (0.66-0.79) in all readers.Conclusion: Some imaging features of whole-tumor and radiomics-predictive model had higher diagnostic performance than one-point. The diagnostic performance of imaging features from whole-tumor alone varied depending on operator experience. Operator experience appears less likely to affect diagnostic performance in the radiomics-predictive model. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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