HYAL1 Is Downregulated in Idiopathic Pulmonary Fibrosis and Inhibits HFL-1 Fibroblast Proliferation When Upregulated.

Background. Idiopathic pulmonary fibrosis (IPF), the most common interstitial lung disease, arises from transforming growth factor beta 1- (TGFβ1-) induced aberrant fibroproliferation in response to epithelial injury. The TGFβ1 antagonists—hyaluronidases (HYALs)—have been used to clinically treat pu...

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Detalles Bibliográficos
Publicado en:BioMed Research International pp. 1 - 16
Autores principales: Leng, Dong, Huang, Xiaoxi, Yi, Jiawen, Zhao, Hongying, Zhang, Yuhui
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 3/11/2020
Acceso en línea:Ver este registro en EBSCOhost