Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody.
Purpose: Despite remarkable clinical responses and prolonged survival across several cancers, not all patients benefit from PD-1/PD-L1 immune checkpoint blockade. Accordingly, assessment of tumour PD-L1 expression by immunohistochemistry (IHC) is increasingly applied to guide patient selection, ther...
| Publicado en: | European Journal of Nuclear Medicine & Molecular Imaging Vol. 47; no. 5; pp. 1302 - 1314 |
|---|---|
| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
May2020
|
| Acceso en línea: | Ver este registro en EBSCOhost |