Accessing a New Dimension in TP53 Biology: Multiplex Long Amplicon Digital PCR to Specifically Detect and Quantitate Individual TP53 Transcripts.

TP53, the most commonly-mutated gene in cancer, undergoes complex alternative splicing. Different TP53 transcripts play different biological roles, both in normal function and in the progression of diseases such as cancer. The study of TP53's alternative RNA splice forms and their use as clinical bi...

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Detalles Bibliográficos
Publicado en:Cancers Vol. 12; no. 3; pp. 769 - 770
Autores principales: Lasham, Annette, Tsai, Peter, Fitzgerald, Sandra J., Mehta, Sunali Y., Knowlton, Nicholas S., Braithwaite, Antony W., Print, Cristin G.
Formato: research tables/charts Journal Article
Publicado: MDPI Mar2020
Acceso en línea:Ver este registro en EBSCOhost