Who benefits from the intervention? Correlates of successful BMI reduction in the Texas Childhood Obesity Demonstration Project (TX‐CORD).

Background: Many childhood obesity intervention studies report mean outcomes but do not explore the variation in responses and the characteristics of those who respond well. Objective: To identify child and family characteristics associated with improvement in the primary outcome, %BMIp95, of the Te...

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Publicado en:Pediatric Obesity Vol. 15; no. 5; pp. 1 - 9
Autores principales: Barlow, Sarah E., Durand, Casey, Salahuddin, Meliha, Pont, Stephen J., Butte, Nancy F., Hoelscher, Deanna M.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell May2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2020
      vid: 15
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/ijpo.12609
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        atl: Who benefits from the intervention? Correlates of successful BMI reduction in the Texas Childhood Obesity Demonstration Project (TX‐CORD).
      aug:
        au:
          Barlow, Sarah E.
          Durand, Casey
          Salahuddin, Meliha
          Pont, Stephen J.
          Butte, Nancy F.
          Hoelscher, Deanna M.
        affil: Baylor College of Medicine, Houston Texas
      sug:
        subj:
          Pediatric Obesity Therapy
          Body Mass Index Texas
          Weight Reduction Programs Texas
          Community Health Services Texas
          Family Characteristics
          Human
          Texas
          Child, Preschool
          Child
          Structural Equation Modeling
          Regression
          Severity of Illness
          Membership
          Odds Ratio
          Age Factors
          Mothers
          Female
          Treatment Outcomes
          Secondary Analysis
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Female
      ab: Background: Many childhood obesity intervention studies report mean outcomes but do not explore the variation in responses and the characteristics of those who respond well. Objective: To identify child and family characteristics associated with improvement in the primary outcome, %BMIp95, of the Texas Childhood Obesity Research Demonstration project (TX‐CORD). Methods: The 12‐month TX‐CORD secondary prevention study randomized 549 children, ages 2 to 12 years, with BMI ≥85th percentile to the intensive intervention vs. the comparison program, with measurements at baseline, 3‐, and 12‐months. A growth mixture model was used to identify mutually exclusive latent %BMIp95 trajectories. Latent class regression tested associations between baseline characteristics and latent class membership. Results: A 2‐class solution emerged after accounting for the effect of intervention randomization. Latent Class 1 participants (86% of sample) were characterized by mild‐to‐moderate obesity and demonstrated a significantly greater response to the intensive intervention between 0 and 3 months (slope‐on‐group = −0.931, p = 0.03). A rebound between 3 and 12 months was not significantly different between arms. Latent Class 2 participants (14%), who had severe obesity, demonstrated no difference in response between intervention groups. Characteristics associated with Class 1 membership included younger age (2–5 years vs. 6–12 years: OR 3.70, p =.035) and lower maternal BMI category (< 35 kg/m2 vs. ≥ 35 kg/m2: OR 7.14, p <.0001). Conclusions: The optimal target population for the intensive intervention are children who have milder obesity, are younger, and do not have a mother with severe obesity. Children with severe obesity may require different approaches.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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