Dual-layer detector spectral CT versus magnetic resonance imaging for the assessment of iron overload in myelodysplastic syndromes and aplastic anemia.
Background: The purpose of this study is to investigate the performance of dual-layer detector spectral CT for iron deposition compared to magnetic resonance imaging (MRI) T2* imaging.Methods: Thirty-one patients with a clinical history of myelodysplastic syndromes and aplastic anemia underwent live...
| Publicado en: | Japanese Journal of Radiology Vol. 38; no. 4; pp. 374 - 382 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Apr2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142683697&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142683697 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Apr2020 vid: 38 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 142683697 142683697 NLM31989387 10.1007/s11604-020-00921-9 NLM31989387 142683697 ppf: 374 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Dual-layer detector spectral CT versus magnetic resonance imaging for the assessment of iron overload in myelodysplastic syndromes and aplastic anemia. aug: au: Ma, Quanmei Hu, Juan Yang, Wei Hou, Yang affil: Department of Radiology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, 110004, Shenyang, Liaoning, People's Republic of China sug: subj: Anemia, Aplastic Tomography, X-Ray Computed Methods Iron Overload Myelodysplastic Syndromes Magnetic Resonance Imaging Methods Aged Male Algorithms Female Prospective Studies Liver Heart Middle Age Adult Scales Aged: 65+ years Middle Aged: 45-64 years Adult: 19-44 years Male Female ab: Background: The purpose of this study is to investigate the performance of dual-layer detector spectral CT for iron deposition compared to magnetic resonance imaging (MRI) T2* imaging.Methods: Thirty-one patients with a clinical history of myelodysplastic syndromes and aplastic anemia underwent liver and cardiac T2*-weighted unenhanced MRI on a three-tesla MRI scanner, and underwent unenhanced CT scan laterally on a 128-row spectral detector CT. R2* values of the liver, septal muscle, and paraspinal muscle were calculated. Attenuation differences (ΔH) in the liver and myocardium were calculated between the lower (50 keV) and higher (120 keV) energy levels.Results: The liver and cardiac T2* values were 9.54 ± 5.63 ms and 21.41 ± 2.44 ms, respectively. The liver-to-muscle and myocardium-to-muscle T2* value ratios were 0.37 ± 0.23 and 0.79 ± 0.19, respectively. The liver and cardiac ΔH were - 1.13 ± 4.24 HU and 2.22 ± 4.41 HU, respectively. There was a strong linear correlation between the liver R2* and ΔH (r = - 0.832, P < 0.001), but weak correlation existed between the cardiac R2* and ΔH (P = 0.041).Conclusions: Dual-layer detector spectral unenhanced CT seemed to be equally valuable to MRI T2* imaging for evaluating liver iron overload. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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