A deep convolutional neural network architecture for interstitial lung disease pattern classification.

Interstitial lung disease (ILD) refers to a group of various abnormal inflammations of lung tissues and early diagnosis of these disease patterns is crucial for the treatment. Yet it is difficult to make an accurate diagnosis due to the similarity among the clinical manifestations of these diseases....

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Publicado en:Medical & Biological Engineering & Computing Vol. 58; no. 4; pp. 725 - 738
Autores principales: Huang, Sheng, Lee, Feifei, Miao, Ran, Si, Qin, Lu, Chaowen, Chen, Qiu
Formato: Journal Article
Publicado: Springer Nature Apr2020
Acceso en línea:Ver este registro en EBSCOhost
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        atl: A deep convolutional neural network architecture for interstitial lung disease pattern classification.
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        au:
          Huang, Sheng
          Lee, Feifei
          Miao, Ran
          Si, Qin
          Lu, Chaowen
          Chen, Qiu
        affil: Department of Control Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China
      sug:
        subj:
          Lung Diseases, Interstitial
          Diagnosis, Computer Assisted Methods
          Resource Databases
          Tomography, X-Ray Computed
          Scales
      ab: Interstitial lung disease (ILD) refers to a group of various abnormal inflammations of lung tissues and early diagnosis of these disease patterns is crucial for the treatment. Yet it is difficult to make an accurate diagnosis due to the similarity among the clinical manifestations of these diseases. In order to assist the radiologists, computer-aided diagnosis systems have been developed. Besides, the potential of deep convolutional neural networks (CNNs) is also expected to exert on the medical image analysis in recent years. In this paper, we design a new deep convolutional neural network (CNN) architecture to achieve the classification task of ILD patterns. Furthermore, we also propose a novel two-stage transfer learning (TSTL) method to deal with the problem of the lack of training data, which leverages the knowledge learned from sufficient textural source data and auxiliary unlabeled lung CT data to the target domain. We adopt the unsupervised manner to learn the unlabeled data, by which the objective function composed of the prediction confidence and mutual information are optimized. The experimental results show that our proposed CNN architecture achieves desirable performance and outperforms most of the state-of-the-art ones. The comparative analysis demonstrates the promising feasibility and advantages of the proposed two-stage transfer learning strategy as well as the potential of the knowledge learning from lung CT data. Graphical Abstract The framework of the proposed two-stage transfer learning method.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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