Diagnostic and management considerations in the modern patient with AIDS: a case of concurrent disseminated Kaposi sarcoma and colesional Cryptococcus neoformans.
In the era of highly active antiretroviral therapy (HAART), disseminated Kaposi sarcoma (KS) has become much rarer in the USA. We report a case of a 34-year- old man with KS of the skin, oropharynx, lung and rectum. Within the same lung nodule, we discovered significant burden of colesional Cryptoco...
| Publicado en: | BMJ Case Reports Vol. 13; no. 4; pp. 1 - 5 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
BMJ Publishing Group
4/14/2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142746666&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142746666 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1757790X B755 jtl: BMJ Case Reports issn: 1757790X maglogo: N pubinfo: dt: 4/14/2020 vid: 13 iid: 4 pid: 8280 pub: BMJ Publishing Group artinfo: ui: 142746666 10.1136/bcr-2019-233860 142746666 ppf: 1 ppct: 4 formats: tig: atl: Diagnostic and management considerations in the modern patient with AIDS: a case of concurrent disseminated Kaposi sarcoma and colesional Cryptococcus neoformans. aug: au: Williams, Samuel Clay Sweeney, Jacob Parameswaran, Lalitha affil: Tri-Institutional MD PhD Program, Weill Cornell Medical College, New York, New York, USA. sug: ab: In the era of highly active antiretroviral therapy (HAART), disseminated Kaposi sarcoma (KS) has become much rarer in the USA. We report a case of a 34-year- old man with KS of the skin, oropharynx, lung and rectum. Within the same lung nodule, we discovered significant burden of colesional Cryptococcus neoformans, in the context of a positive asymptomatic cryptococcal antigenemia, which was a previously unreported occurrence. The gold standard of treatment for KS continues to be HAART. The role of chemotherapy is still controversial. In addition, a cryptococcal antigen screen-and- treat approach with fluconazole is still not routinely recommended in the USA to prevent serious meningeal disease despite recent studies showing efficacy and applicability. We discuss both issues here and the outcome of our patient. We also present the patient’s own unique perspective in dealing with the ramifications of these diagnoses. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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