Three-Dimensional Texture Feature Analysis of Pulmonary Nodules in CT Images: Lung Cancer Predictive Models Based on Support Vector Machine Classifier.

To extract texture features of pulmonary nodules from three-dimensional views and to assess if predictive models of lung CT images from a three-dimensional texture feature could improve assessments conducted by radiologists. Clinical and CT imaging data for three dimensions (axial, coronal, and sagi...

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Publicado en:Journal of Digital Imaging Vol. 33; no. 2; pp. 414 - 423
Autores principales: Gao, Ni, Tian, Sijia, Li, Xia, Huang, Jian, Wang, Jingjing, Chen, Sipeng, Ma, Yuan, Liu, Xiangtong, Guo, Xiuhua
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Apr2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-019-00238-8
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        atl: Three-Dimensional Texture Feature Analysis of Pulmonary Nodules in CT Images: Lung Cancer Predictive Models Based on Support Vector Machine Classifier.
      aug:
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          Gao, Ni
          Tian, Sijia
          Li, Xia
          Huang, Jian
          Wang, Jingjing
          Chen, Sipeng
          Ma, Yuan
          Liu, Xiangtong
          Guo, Xiuhua
        affil: School of Public Health, Capital Medical University, 100069, Beijing, China
      sug:
        subj:
          Tomography, X-Ray Computed Methods
          Imaging, Three-Dimensional Methods
          Lung Neoplasms Radiography
          Support Vector Machine
          Human
          Radiologists
          Sensitivity and Specificity
          Models, Statistical
          ROC Curve
          Middle Age
          Aged, 80 and Over
          Male
          Female
          Aged
          Middle Aged: 45-64 years
          Aged, 80 & over
          Aged: 65+ years
          Male
          Female
      ab: To extract texture features of pulmonary nodules from three-dimensional views and to assess if predictive models of lung CT images from a three-dimensional texture feature could improve assessments conducted by radiologists. Clinical and CT imaging data for three dimensions (axial, coronal, and sagittal) in pulmonary nodules in 285 patients were collected from multiple centers and the Cancer Imaging Archive after ethics committee approval. Three-dimensional texture feature values (contourlets), and clinical and computed tomography (CT) imaging data were built into support vector machine (SVM) models to predict lung cancer, using four evaluation methods (disjunctive, conjunctive, voting, and synthetic); sensitivity, specificity, the Youden index, discriminant power (DP), and F value were calculated to assess model effectiveness. Additionally, diagnostic accuracy (three-dimensional model, axial model, and radiologist assessment) was assessed using the area under the curves for receiver operating characteristic (ROC) curves. Cross-sectional data from 285 patients (median age, 62 [range, 45–83] years; 115 males [40.4%]) were evaluated. Integrating three-dimensional assessments, the voting method had relatively high effectiveness based on both sensitivity (0.98) and specificity (0.79), which could improve radiologist diagnosis (maximum sensitivity, 0.75; maximum specificity, 0.51) for 23% and 28% respectively. Furthermore, the three-dimensional texture feature model of the voting method has the best diagnosis of precision rate (95.4%). Of all three-dimensional texture feature methods, the result of the voting method was the best, maintaining both high sensitivity and specificity scores. Additionally, the three-dimensional texture feature models were superior to two-dimensional models and radiologist-based assessments.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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