Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI.
Objective: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possible to determine a threshold velocity value to class...
| Publicado en: | Skeletal Radiology Vol. 49; no. 6; pp. 869 - 882 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jun2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142815883&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142815883 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: Jun2020 vid: 49 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 142815883 142815883 NLM31897519 10.1007/s00256-019-03363-1 NLM31897519 142815883 ppf: 869 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Characterization of soft tissue tumours with ultrasound, shear wave elastography and MRI. aug: au: Winn, N. Baldwin, J. Cassar-Pullicino, V. Cool, P. Ockendon, M. Tins, B. Jaremko, J. L. affil: The Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Foundation Trust, SY10 7AG, Oswestry, UK sug: subj: Ultrasonography Methods Soft Tissue Neoplasms Magnetic Resonance Imaging Methods Aged Adult Prospective Studies Middle Age Female Soft Tissue Neoplasms Pathology Male Biopsy Aged, 80 and Over Adolescence Aged: 65+ years Adult: 19-44 years Middle Aged: 45-64 years Aged, 80 & over Adolescent: 13-18 years Female Male ab: Objective: To predict accurately whether a soft tissue mass was benign or malignant and to characterize its type using ultrasound, shear wave elastography and MRI. We hypothesized that with the addition of shear wave elastography, it would be possible to determine a threshold velocity value to classify a lesion as benign or malignant.Materials and Methods: A total of 151 consecutive, consenting adult patients were prospectively recruited to this study in a tertiary referral musculoskeletal oncology centre. All lesions were assessed with ultrasound, including B mode, Doppler and shear wave elastography measurements. One hundred thirty-eight patients also underwent MRI of the lesion. A histological diagnosis was obtained for all lesions.Results: Malignant lesions were larger than benign lesions and had a greater Doppler activity. There was no useful threshold shear wave velocity to differentiate between benign and malignant lesions. Longitudinal and transverse shear wave velocities were strongly positively correlated with each other. An inverse correlation was shown with lesion size and depth, regardless of whether it was benign or malignant. A logistic regression model combining the ultrasound and MRI characteristics did not confidently classify a lesion as benign or malignant and was inferior to expert opinion.Conclusion: The strongest predictors of malignancy are large lesion size and high vascularity. The combination of all ultrasound characteristics (including shear wave elastography) and MRI features does not confidently classify a lesion as benign or malignant, and histological diagnosis remains the gold standard. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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