Feasibility of a randomized controlled trial of symptom screening and feedback to healthcare providers compared with standard of care using the SPARK platform.

Purpose: Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK) is a web-based application that enables symptom screening and access to clinical practice guidelines for symptom management. Objective was to determine the feasibility of a randomized trial of daily symptom scre...

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Publicado en:Supportive Care in Cancer Vol. 28; no. 6; pp. 2729 - 2735
Autores principales: Cook, Sadie, Vettese, Emily, Tomlinson, George A., Soman, Dilip, Schechter, Tal, Kuczynski, Susan, Gladstone, Brenda, Dupuis, L. Lee, Sung, Lillian
Formato: research randomized controlled trial Journal Article
Publicado: Springer Nature Jun2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2020
      vid: 28
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00520-019-05115-2
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        atl: Feasibility of a randomized controlled trial of symptom screening and feedback to healthcare providers compared with standard of care using the SPARK platform.
      aug:
        au:
          Cook, Sadie
          Vettese, Emily
          Tomlinson, George A.
          Soman, Dilip
          Schechter, Tal
          Kuczynski, Susan
          Gladstone, Brenda
          Dupuis, L. Lee
          Sung, Lillian
        affil: Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Peter Gilgan Centre for Research and Learning, 686 Bay Street, M5G 0A4, Toronto, Ontario, Canada
      sug:
        subj:
          Hematopoietic Stem Cell Transplantation Methods
          Neoplasms Therapy
          Quality of Health Care
          Adverse Drug Event
          Research
          Palliative Care Methods
          Human
          Multidisciplinary Care Team
          Female
          Pilot Studies
          Male
          Health Screening Methods
          Health Personnel
          Child
          Adolescence
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Randomized Controlled Trials
          Scales
          Child: 6-12 years
          Adolescent: 13-18 years
          Female
          Male
      ab: Purpose: Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK) is a web-based application that enables symptom screening and access to clinical practice guidelines for symptom management. Objective was to determine the feasibility of a randomized trial of daily symptom screening for 5 days among children receiving cancer treatments.Methods: We included English-speaking pediatric cancer and hematopoietic stem cell transplantation (HSCT) patients who were 8-18 years of age at enrollment and who were expected to be in the hospital or in clinic daily for five consecutive days. We randomized children to either undergo daily symptom screening with symptom reports provided to the healthcare team using the SPARK vs. standard of care. The primary endpoint was feasibility, defined as being able to enroll at least 30 participants within 1 year, and among those randomized to intervention, at least 75% completing symptom screening on at least 60% of on-study days.Results: From July 2018 to November 2018, we enrolled and randomized 30 participants. The median age at enrollment was 12.5 (range 8-18) years. Among the intervention group, the median number of days Symptom Screening in Pediatrics Tool (SSPedi) was completed at least once was 5 (range 4 to 5), with one participant missing 1 day of symptom screening. Among all participants, baseline and day 5 SSPedi scores were obtained in 29/30 participants.Conclusion: A randomized trial of the SPARK with daily symptom screening for 5 days was feasible. It is now appropriate to proceed toward a definitive multi-center trial to test the efficacy of SPARK to improve symptom control.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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