Peripheral Vein Thrombophlebitis in the Upper Extremity: A Systematic Review of a Frequent and Important Problem.

Background: The acceptable incidence of thrombophlebitis following intravenous cannulation is 5%, as recommended by the Intravenous Nurses Society guidelines, but publications have reported startling figures of 20% to 80%. Given the frequency of intravenous lines, this presents a potential clinical...

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Publicado en:American Journal of Medicine Vol. 133; no. 4; pp. 473 - 474
Autores principales: Heng, Shu Yun, Yap, Robert Tze-Jin, Tie, Joyce, McGrouther, Duncan Angus
Formato: research systematic review Journal Article
Publicado: Excerpta Medica Publishing Group Apr2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2020
      vid: 133
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      pub: Excerpta Medica Publishing Group
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        142883739
        10.1016/j.amjmed.2019.08.054
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        142883739
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        atl: Peripheral Vein Thrombophlebitis in the Upper Extremity: A Systematic Review of a Frequent and Important Problem.
      aug:
        au:
          Heng, Shu Yun
          Yap, Robert Tze-Jin
          Tie, Joyce
          McGrouther, Duncan Angus
        affil: Department of Hand and Reconstructive Microsurgery, Singapore General Hospital, Singapore
      sug:
        subj:
          Thrombophlebitis Etiology
          Upper Extremity
          Risk Factors
          Catheterization, Peripheral Adverse Effects
          Thrombophlebitis Prevention and Control
          Human
          Systematic Review
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
      ab: Background: The acceptable incidence of thrombophlebitis following intravenous cannulation is 5%, as recommended by the Intravenous Nurses Society guidelines, but publications have reported startling figures of 20% to 80%. Given the frequency of intravenous lines, this presents a potential clinical problem. We aimed to determine the predisposing patient, catheter, and health care-related factors of peripheral vein thrombophlebitis in the upper extremity.Methods: In this systematic review, we used a comprehensive search strategy to identify risk factors of thrombophlebitis from inception to May 20, 2019. Studies reporting risk factors of peripheral vein thrombophlebitis of adult patients admitted to the hospital and receiving an intravenous cannulation were included. The Quality of Prognostic Studies tool was used in the assessment for risk of bias to determine the study quality.Results: Of the 6910 studies initially identified, 25 were eligible for inclusion. Qualitative syntheses revealed that patient-related factors that confer a higher risk included intercurrent illness, immunocompromised state, comorbidities such as diabetes mellitus, malignancy, previous thrombophlebitis, burns, and higher hemoglobin levels. Catheter-related risk factors included catheter size, duration, and site of insertion. Intravenous antibiotics and potassium chloride predisposed to thrombophlebitis. Cannulation by an intravenous therapy team and more nursing care were associated with a decreased risk. A P-value < .5 was considered to be statistically significant.Conclusion: Recognition of the predisposing factors would allow for targeted strategies to aid in the prevention of this iatrogenic infection, which may include closer monitoring of patients who are identified to be vulnerable. Based on this systematic review, we developed an algorithm to guide clinical management. Further research is warranted to validate this algorithm.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        Journal Article
      ougenre: Article
    language: English
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