Preoperative localization of sentinel lymph node in breast cancer patients by silver wire insertion or liquid charcoal injection guided by CT lymphography.

Dual localization of SLN in breast cancer patients using isotope & dye is the best‐approved modality with limitations such as high cost of radioactive materials, complex logistic preparations & scheduling issues, especially in developing countries. We investigated the feasibility & accuracy of a nov...

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Published in:Breast Journal Vol. 26; no. 4; pp. 617 - 625
Main Authors: Hamdy, Omar, El‐Badrawy, Adel, Saleh, Gehad A., Metwally, Islam H., Abdelwahab, Khaled, Farouk, Omar, Denewer, Adel, Setit, Ahmed
Format: diagnostic images pictorial research tables/charts Journal Article
Published: Wiley-Blackwell Apr2020
Online Access:View this record in EBSCOhost
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      dt: Apr2020
      vid: 26
      iid: 4
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/tbj.13511
        142907076
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      tig:
        atl: Preoperative localization of sentinel lymph node in breast cancer patients by silver wire insertion or liquid charcoal injection guided by CT lymphography.
      aug:
        au:
          Hamdy, Omar
          El‐Badrawy, Adel
          Saleh, Gehad A.
          Metwally, Islam H.
          Abdelwahab, Khaled
          Farouk, Omar
          Denewer, Adel
          Setit, Ahmed
        affil: Surgical Oncology Unit, Oncology Center, Mansoura University, Mansoura, Egypt
      sug:
        subj:
          Preoperative Care Methods
          Breast Neoplasms Diagnosis
          Sentinel Lymph Node Biopsy Methods
          Charcoal Diagnostic Use
          Silver Diagnostic Use
          Human
          Charcoal Administration and Dosage
          Tomography, X-Ray Computed Methods
          Lymphography Methods
          Methylene Blue Diagnostic Use
          Descriptive Statistics
      ab: Dual localization of SLN in breast cancer patients using isotope & dye is the best‐approved modality with limitations such as high cost of radioactive materials, complex logistic preparations & scheduling issues, especially in developing countries. We investigated the feasibility & accuracy of a novel technique for SLN localization using silver wire insertion or liquid charcoal injection guided by CT lymphography. 120 patients with clinically node‐negative breast cancer were enrolled. In the test group, SLN was localized using preoperative CTLG guided injection of liquid charcoal or by placing a 3 cm silver wire. In addition, intraoperative SLN mapping was performed using methylene blue dye followed by searching for the SLN localized by both methods. In the control group, SLN was localized by the blue dye only. Feasibility, accuracy, detection rates, and number of SLNs retrieved were reported as well as matching between the LN detected with the CTLG and that detected with the dye technique. SLN could be detected in 59 out of 60 patients (98.3%) in the test group and in 54 out of 60 patients (90%) in the control group (P =.057). In self‐controlled analysis of the test group comparing CTLG only to dye only was significant (P =.050). Comparing charcoal to silver wire in detection was statistically insignificant (P =.5). This novel method can offer advantages which are as follows: being more accurate than the dye alone, saving operative time, abandoning complex logistic preparations for the radioisotope, and solving the problem of timing.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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