International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.
Background: The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) has developed computerised adaptive tests (CATs) for the 14 functional and symptom domains of the EORTC QLQ-C30 quality of life questionnaire. This is expected to optimise measurement preci...
| Published in: | Quality of Life Research Vol. 29; no. 5; pp. 1405 - 1418 |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Published: |
Springer Nature
May2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=142973622&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 142973622 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09629343 GPQ jtl: Quality of Life Research issn: 09629343 maglogo: N pubinfo: dt: May2020 vid: 29 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 142973622 142973622 NLM31955374 10.1007/s11136-020-02421-9 NLM31955374 142973622 ppf: 1405 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer. aug: au: Petersen, Morten Aa. Aaronson, Neil K. Conroy, Thierry Costantini, Anna Giesinger, Johannes M. Hammerlid, Eva Holzner, Bernhard Johnson, Colin D. Kieffer, Jacobien M. van Leeuwen, Marieke Nolte, Sandra Ramage, John K. Tomaszewski, Krzysztof A. Waldmann, Annika Young, Teresa Zotti, Paola Groenvold, Mogens affil: The Research Unit, Department of Palliative Medicine, Bispebjerg & Frederiksberg Hospital, University of Copenhagen, Bispebjerg bakke 23B, 2400, Copenhagen NV, Denmark sug: subj: Quality of Life Psychosocial Factors Psychometrics Methods Neoplasms Psychosocial Factors Female Male Neoplasms Diagnosis Adult Aged Europe Computers and Computerization Sample Size Cross Sectional Studies Middle Age Algorithms Questionnaires Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Background: The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group (QLG) has developed computerised adaptive tests (CATs) for the 14 functional and symptom domains of the EORTC QLQ-C30 quality of life questionnaire. This is expected to optimise measurement precision, relevance to patients and flexibility. Here, we present the first international validation of the EORTC CAT Core.Methods: A heterogeneous sample of 699 cancer patients scheduled for chemotherapy and/or radiotherapy was recruited across seven European countries. The EORTC CAT Core and all QLQ-C30 items were administered to participants before and after initiating treatment. Correlations between CAT and QLQ-C30 scores and floor/ceiling effects were calculated. Using several grouping variables, relative validity (cross-sectional known groups difference), responsiveness (changes over time) and relative sample size requirements of the CAT compared to the QLQ-C30 were estimated.Results: Correlations of the CAT and QLQ-C30 ranged from 0.81 to 0.93 across domains. The mean relative reduction in floor and ceiling effects using the CAT was 42% (range 3-99%). Analyses of known groups validity and responsiveness indicated that, across domains, mean sample size requirements for the CAT were 72% and 70%, respectively, of those using the QLQ-C30.Conclusions: The EORTC CAT Core measures the same domains as the QLQ-C30 with reduced floor/ceiling effects. The CAT generally facilitated the use of smaller samples (about 30% smaller on average) without loss of power compared to the QLQ-C30. Based on this study, the EORTC QLG will release the EORTC CAT Core for general use. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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