Detection of Diabetic Macular Edema in Optical Coherence Tomography Image Using an Improved Level Set Algorithm.

Diabetic macular edema (DME) is a major cause of visual loss in the patients with diabetic retinopathy. DME detection in Optical Coherence Tomography (OCT) image contributes to the early diagnosis of diabetic retinopathy and blindness prevention. Currently, DME detection in the OCT image mainly reli...

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Publicado en:BioMed Research International pp. 1 - 8
Autores principales: Wang, Zhenhua, Zhang, Wenping, Sun, Yanan, Yao, Mudi, Yan, Biao
Formato: algorithm diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 4/30/2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 4/30/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/6974215
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        atl: Detection of Diabetic Macular Edema in Optical Coherence Tomography Image Using an Improved Level Set Algorithm.
      aug:
        au:
          Wang, Zhenhua
          Zhang, Wenping
          Sun, Yanan
          Yao, Mudi
          Yan, Biao
        affil: College of Information Science, Shanghai Ocean University, Shanghai 201306, China
      sug:
        subj:
          Diabetic Retinopathy Diagnosis
          Macular Edema Diagnosis
          Algorithms
          Tomography, Optical Coherence
          Sensitivity and Specificity
          Precision
          Human
      ab: Diabetic macular edema (DME) is a major cause of visual loss in the patients with diabetic retinopathy. DME detection in Optical Coherence Tomography (OCT) image contributes to the early diagnosis of diabetic retinopathy and blindness prevention. Currently, DME detection in the OCT image mainly relies on the handwork by the experienced clinician. It is a laborious, time-consuming, and challenging work to organize a comprehensive DME screening for diabetic patients. In this study, we proposed a novel algorithm for the detection and segmentation of DME region in OCT image based on the K-means clustering algorithm and improved Selective Binary and Gaussian Filtering regularized level set (SBGFRLS) algorithm named as SBGFRLS-OCT algorithm. SBGFRLS-OCT algorithm was compared with the current level set algorithms, including C-V (Chan-Vese), GAC (geodesic active contour), and SBGFRLS, to estimate the performance of DME detection. SBGFRLS-OCT algorithm was also compared with the clinician to estimate the precision, sensitivity, and specificity of DME segmentation. Compared with C-V, GAC, and SBGFRLS algorithm, the SBGFRLS-OCT algorithm enhanced the accuracy and reduces the processing time of DME detection. Compared with manual DME segmentation, the SBGFRLS-OCT algorithm achieved a comparable precision (97.7%), sensitivity (91.8%), and specificity (99.2%). Collectively, this study presents a novel algorithm for DME detection in the OCT image, which can be used for mass diabetic retinopathy screening.
      pubtype: Academic Journal
      doctype:
        algorithm
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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