Dysfunctional polycomb transcriptional repression contributes to lamin A/C-dependent muscular dystrophy.

Lamin A is a component of the inner nuclear membrane that, together with epigenetic factors, organizes the genome in higher order structures required for transcriptional control. Mutations in the lamin A/C gene cause several diseases belonging to the class of laminopathies, including muscular dystro...

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Publicado en:	Journal of Clinical Investigation Vol. 130; no. 5; pp. 2408 - 2422
Autores principales:	Bianchi, Andrea, Mozzetta, Chiara, Pegoli, Gloria, Lucini, Federica, Valsoni, Sara, Rosti, Valentina, Petrini, Cristiano, Cortesi, Alice, Gregoretti, Francesco, Antonelli, Laura, Oliva, Gennaro, De Bardi, Marco, Rizzi, Roberto, Bodega, Beatrice, Pasini, Diego, Ferrari, Francesco, Bearzi, Claudia, Lanzuolo, Chiara
Formato:	research Journal Article
Publicado:	American Society for Clinical Investigation May2020
Acceso en línea:	Ver este registro en EBSCOhost