Testing the repatriated for SARS-Cov2: Should laboratory-based quarantine replace traditional quarantine?

An ongoing epidemic of respiratory diseases caused by a novel coronavirus (COVID 2019, SARS-CoV2) started in Wuhan, Hubei, in China at the end of December 2019. The French government decided to repatriate the 337 French nationals living in Wuhan and place them in quarantine in their home country. We...

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Published in:Travel Medicine & Infectious Disease Vol. 34
Main Authors: Lagier, Jean Christophe, Colson, Philippe, Tissot Dupont, Hervé, Salomon, Jérôme, Doudier, Barbara, Aubry, Camille, Gouriet, Frédérique, Baron, Sophie, Dudouet, Pierre, Flores, Rémi, Ailhaud, Lucie, Gautret, Philippe, Parola, Philippe, La Scola, Bernard, Raoult, Didier, Brouqui, Philippe
Format: research tables/charts Journal Article
Published: Elsevier B.V. Mar2020
Online Access:View this record in EBSCOhost
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      dt: Mar2020
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        atl: Testing the repatriated for SARS-Cov2: Should laboratory-based quarantine replace traditional quarantine?
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        au:
          Lagier, Jean Christophe
          Colson, Philippe
          Tissot Dupont, Hervé
          Salomon, Jérôme
          Doudier, Barbara
          Aubry, Camille
          Gouriet, Frédérique
          Baron, Sophie
          Dudouet, Pierre
          Flores, Rémi
          Ailhaud, Lucie
          Gautret, Philippe
          Parola, Philippe
          La Scola, Bernard
          Raoult, Didier
          Brouqui, Philippe
        affil: Aix Marseille Univ, IRD, AP-HM, MEPHI, IHU Méditerranée Infection, Marseille, France
      sug:
        subj:
          Health Screening
          Severe Acute Respiratory Syndrome Prevention and Control
          COVID-19 Prevention and Control
          Quarantine
          Anxiety Prevention and Control
          Human
          France
          RNA Analysis
          Reverse Transcriptase Polymerase Chain Reaction
          Sputum
          Male
          Female
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          Adult
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          Infant, Newborn
          Decision Making
          Funding Source
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          Child, Preschool: 2-5 years
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Infant, Newborn: birth-1 month
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      ab: An ongoing epidemic of respiratory diseases caused by a novel coronavirus (COVID 2019, SARS-CoV2) started in Wuhan, Hubei, in China at the end of December 2019. The French government decided to repatriate the 337 French nationals living in Wuhan and place them in quarantine in their home country. We decided to test them all for SARS-Cov2 twice in order to reduce anxiety among the population and decision-makers. We investigated the presence of SARS-CoV-19 in asymptomatic carriers by testing all repatriated patients within the first 24 h of their arrival in France and at day 5. Viral RNA was extracted from pooled nasal and oropharyngeal swab fluids or sputum in the absence of nasal/oropharyngeal swabs. Detection of SARS-CoV-2 RNA was then carried out using several real-time reverse transcription (RT)-PCR assays. We tested 337 passengers at day 0 and day 5. All the tests for SARS-CoV2 were negative. By optimising the sampling process, sending samples sequentially and reducing the time-scale for biological analysis, we were able to test the samples within 5 h (including sampling, shipment and biological tests). Optimising our procedures reduces anxiety and reassures the population and decision makers.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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