Development of a Lung Rescue Team to Improve Care of Subjects With Refractory Acute Respiratory Failure.

BACKGROUND: A lung-protective mechanical ventilation strategy has become the hallmark of ventilation management for patients with acute respiratory failure. However, some patients progress to more severe forms of acute respiratory failure with refractory hypoxemia. In such circumstances, individuali...

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Publicado en:Respiratory Care Vol. 65; no. 4; pp. 420 - 427
Autores principales: Spina, Stefano, Capriles, Martin, De Santis Santiago, Roberta, Florio, Gaetano, Teggia-Droghi, Maddalena, Grassi, Luigi, Hu, Jie, Kelley, Rosemary, Bittner, Edward A., Kacmarek, Robert M., Berra, Lorenzo
Formato: CEU research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Apr2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Development of a Lung Rescue Team to Improve Care of Subjects With Refractory Acute Respiratory Failure.
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          Spina, Stefano
          Capriles, Martin
          De Santis Santiago, Roberta
          Florio, Gaetano
          Teggia-Droghi, Maddalena
          Grassi, Luigi
          Hu, Jie
          Kelley, Rosemary
          Bittner, Edward A.
          Kacmarek, Robert M.
          Berra, Lorenzo
        affil: Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
      sug:
        subj:
          Respiratory Failure Therapy
          Quality Improvement
          Respiration, Artificial
          Human
          Education, Continuing (Credit)
          Retrospective Design
          Descriptive Statistics
          Positive End-Expiratory Pressure
          Extracorporeal Membrane Oxygenation
          Manometry
          Echocardiography
          Electric Impedance
          Tomography
          Massachusetts
          Individualized Medicine
          Adult
          Middle Age
          Male
          Female
          Anoxemia Therapy
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: BACKGROUND: A lung-protective mechanical ventilation strategy has become the hallmark of ventilation management for patients with acute respiratory failure. However, some patients progress to more severe forms of acute respiratory failure with refractory hypoxemia. In such circumstances, individualized titration of mechanical ventilation according to the patient's specific respiratory and cardiovascular pathophysiology is desirable. A lung rescue team (LRT) was recently established at our institution to improve the medical care of patients with acute respiratory failure when conventional treatment fails. The aim of this report is to describe the consultation processes, the cardiopulmonary assessment, and the procedures of the LRT. METHODS: This was a retrospective review of the LRT management of patients with acute respiratory failure and refractory hypoxemia at Massachusetts General Hospital in Boston, Massachusetts. The LRT is composed of a critical care physician, the ICU respiratory therapist on duty, the ICU nurse on duty, and 2 critical care fellows. In the LRT approach, respiratory mechanics are evaluated through lung recruitment maneuvers and decremental PEEP trials by means of 3 tools: esophageal manometry, echocardiography, and electrical impedance tomography lung imaging. RESULTS: The LRT was consulted 89 times from 2014 to 2019 for evaluation and management of severely critically ill patients with acute respiratory failure and refractory hypoxemia on mechanical ventilation. The LRT was requested a median of 2 (interquartile range 1–6) d after intubation to optimize mechanical ventilation and to titrate PEEP in 77 (86%) subjects, to manage ventilation in 8 (9%) subjects on extracorporeal membrane oxygenation (ECMO), and to manage weaning strategy from mechanical ventilation in 4 (5%) subjects. The LRT found consolidations with atelectasis responsive to recruitment maneuvers in 79% (n = 70) of consultations. The LRT findings translated into a change of care in 81% (n = 72) of subjects. CONCLUSIONS: The LRT individualized the management of severe acute respiratory failure. The LRT consultations were shown to be effective, safe, and efficient, with an impact on decision-making in the ICU.
      pubtype: Academic Journal
      doctype:
        CEU
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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