Laboratory Options for Risk Assessment of Pregnancy Pathologies.
The most effective method of screening for chromosomal abnormalities and evaluating the risk of pregnancy pathologies in the first trimester is combined screening. The algorithm of screening is based on the combination of maternal age, measuring of the nuchal translucency and the fetal heart rate an...
| Publicado en: | Physiological Research Vol. 68; pp. 415 - 426 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Institute of Physiology, Academy of Sciences of the Czech Republic
2019Supplement 4
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143202075&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143202075 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08628408 1CVW jtl: Physiological Research issn: 08628408 maglogo: N pubinfo: dt: 2019Supplement 4 vid: 68 pid: 24634 pub: Institute of Physiology, Academy of Sciences of the Czech Republic artinfo: ui: 143202075 10.33549/physiolres.934376 143202075 ppf: 415 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Laboratory Options for Risk Assessment of Pregnancy Pathologies. aug: au: KESTLEROVÁ, A. KROFTA, L. ŽUFIĆ, A. BĚHÁVKOVÁ, K. HAMPLOVÁ RAČKO, J. BENEŠ, J. FEYEREISL, J. affil: Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Prague, Czech Republic sug: ab: The most effective method of screening for chromosomal abnormalities and evaluating the risk of pregnancy pathologies in the first trimester is combined screening. The algorithm of screening is based on the combination of maternal age, measuring of the nuchal translucency and the fetal heart rate and analysis of the placental products of free ß-hCG and PAPP-A. For the screening of preeclampsia, placental growth factor (PlGF) is added. To distinguish between preeclampsia and other pathologies caused by placental dysfunction it is recommended to also extend the screening with selected immunological markers. We concluded that elevated biochemical and immunological markers can help to predict the threat of preeclampsia in the third trimester. Some markers can probably predict the development of particularly severe pathological conditions. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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