Neural negated entity recognition in Spanish electronic health records.

This work deals with negation detection in the context of clinical texts. Negation detection is a key for decision support systems since negated events (detection of absence of some events) help ascertain current medical conditions. For artificial intelligence, negation detection is a valuable point...

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Publicado en:Journal of Biomedical Informatics Vol. 105
Autores principales: Santiso, Sara, Pérez, Alicia, Casillas, Arantza, Oronoz, Maite
Formato: research Journal Article
Publicado: Academic Press Inc. May2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2020
      vid: 105
      pid: 735
      pub: Academic Press Inc.
      place: Burlington, Massachusetts
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        10.1016/j.jbi.2020.103419
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        atl: Neural negated entity recognition in Spanish electronic health records.
      aug:
        au:
          Santiso, Sara
          Pérez, Alicia
          Casillas, Arantza
          Oronoz, Maite
        affil: IXA Group, University of the Basque Country (UPV-EHU), ManuelLardizabal 1, 20080 Donostia, Spain
      sug:
        subj:
          Natural Language Processing
          Artificial Intelligence
          Comparative Studies
          Multicenter Studies
          Evaluation Research
          Validation Studies
          Human
      ab: This work deals with negation detection in the context of clinical texts. Negation detection is a key for decision support systems since negated events (detection of absence of some events) help ascertain current medical conditions. For artificial intelligence, negation detection is a valuable point as it can revert the meaning of a part of a text and, accordingly, influence other tasks such as medical dosage adjustment, the detection of adverse drug reactions or hospital acquired diseases. We focus on negated medical events such as disorders, findings and allergies. From Natural Language Processing (NLP) background, we refer to them as negated medical entities. A novelty of this work is that we approached this task as Named Entity Recognition (NER) with the restriction that just negated medical entities must be recognized (in an attempt to help distinguish them from non-negated ones). Our study is driven with Electronic Health Records (EHRs) written in Spanish. A challenge to cope with is the lexical variability (alternative medical forms, abbreviations, etc.). To this end, we employed an approach based on deep learning. Specifically, the system combines character embeddings to cope with out-of-vocabulary (OOV) words, Long Short-Term Memory (LSTM) networks to model contextual representations and it makes use of Conditional Random Fields (CRF) to classify each medical entity as either negated or not given the contextual dense representation. Moreover, we explored both embeddings created from words and embeddings created from lemmas. The best results were obtained with the lemmatized embeddings. Apparently, this approach reinforced the capability of the LSTMs to cope with the high lexical variability. The f-measure for exact-match was 65.1 and 82.4 for the partial-match.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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