Chondral tumours: discrepancy rate between needle biopsy and surgical histology.
Objective: To determine the reliability of image-guided core needle biopsy (IGCNB) for the diagnosis and grading of chondral tumours of bone compared with surgical histology.Materials and Methods: Retrospective review of patients with a chondral tumour of bone who underwent IGCNB and surgical resect...
| Publicado en: | Skeletal Radiology Vol. 49; no. 7; pp. 1115 - 1126 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143329610&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143329610 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: Jul2020 vid: 49 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 143329610 143329610 NLM32147756 10.1007/s00256-020-03406-y NLM32147756 143329610 ppf: 1115 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Chondral tumours: discrepancy rate between needle biopsy and surgical histology. aug: au: Oliveira, Ines Chavda, Anesh Rajakulasingam, Ramanan Saifuddin, Asif affil: Royal National Orthopaedic Hospital, London, UK sug: subj: Bone Neoplasms Pathology Chondrosarcoma Pathology Bone Neoplasms Surgery Biopsy Chondrosarcoma Surgery Aged, 80 and Over Female Reproducibility of Results Middle Age Retrospective Design Adult Child Male Biopsy, Needle Neoplasm Grading Adolescence Aged Scales Aged, 80 & over Middle Aged: 45-64 years Adult: 19-44 years Child: 6-12 years Adolescent: 13-18 years Aged: 65+ years Female Male ab: Objective: To determine the reliability of image-guided core needle biopsy (IGCNB) for the diagnosis and grading of chondral tumours of bone compared with surgical histology.Materials and Methods: Retrospective review of patients with a chondral tumour of bone who underwent IGCNB and surgical resection between January 2007 and December 2017. Data collected included age, sex, skeletal location, technique used for IGCNB, IGCNB result including histological grade and comparison with surgical histology.Results: A total of 237 patients were included (135 males and 102 females with mean age 53.7 years, range 9-89 years). A total of 174 IGCNBs were CT-guided, 57 ultrasound-guided and 6 fluoroscopic-guided. Two hundred thirty-six of 237 (99.6%) IGCNBs were diagnostic for a chondral tumour, although grade could not be determined in 13 (5.5%) due to necrosis. A positive correlation for tumour grade between IGCNB and surgical histology was achieved in 181 cases (76.4%). In 36 patients (15.2%), IGCNB under-graded the tumour, while in 6 (2.5%), IGCNB over-graded the tumour. Discrepancy between IGCNB and surgical histology was significantly greater for surface/peripheral lesions (p = 0.02) and lesions arising from the flat bones or spine (p = 0.002).Discussion: IGCNB can achieve a diagnosis of a chondral tumour in a high proportion of cases when compared with final diagnosis from surgical resection specimens. However, correlation of tumour grade between IGCNB and resection histology is less reliable with discordance seen in almost one-quarter of cases, most commonly at non-appendicular sites. Therefore, IGCNB results should not be considered in isolation of imaging and clinical features when planning surgical management. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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