Highly accelerated compressed sensing time-of-flight magnetic resonance angiography may be reliable for diagnosing head and neck arterial steno-occlusive disease: a comparative study with digital subtraction angiography.

Introduction: We aimed to investigate the utility of compressed sensing time-of-flight magnetic resonance angiography (CS TOF-MRA) for diagnosing intracranial and cervical arterial stenosis by using digital subtraction angiography (DSA) as the reference standard.Methods: Thirty-seven patients with h...

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Publicado en:European Radiology Vol. 30; no. 6; pp. 3059 - 3066
Autores principales: Zhang, Xuan, Cao, Yue Zhou, Mu, Xi Hu, Sun, Yi, Schmidt, Michaela, Forman, Christoph, Speier, Peter, Lu, Shan Shan, Hong, Xun Ning
Formato: research Journal Article
Publicado: Springer Nature Jun2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        10.1007/s00330-020-06682-3
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        atl: Highly accelerated compressed sensing time-of-flight magnetic resonance angiography may be reliable for diagnosing head and neck arterial steno-occlusive disease: a comparative study with digital subtraction angiography.
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        au:
          Zhang, Xuan
          Cao, Yue Zhou
          Mu, Xi Hu
          Sun, Yi
          Schmidt, Michaela
          Forman, Christoph
          Speier, Peter
          Lu, Shan Shan
          Hong, Xun Ning
        affil: Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guangzhou Road, Gulou district, Nanjing, Jiangsu Province, China
      sug:
        subj:
          Vertebral Artery
          Angiography, Digital Subtraction Methods
          Magnetic Resonance Angiography Methods
          Carotid Arteries
          Arterial Occlusive Diseases Diagnosis
          Middle Age
          Male
          Female
          Retrospective Design
          Reproducibility of Results
          ROC Curve
          Human
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Middle Aged: 45-64 years
          Male
          Female
      ab: Introduction: We aimed to investigate the utility of compressed sensing time-of-flight magnetic resonance angiography (CS TOF-MRA) for diagnosing intracranial and cervical arterial stenosis by using digital subtraction angiography (DSA) as the reference standard.Methods: Thirty-seven patients with head and neck arterial stenoses who underwent CS TOF-MRA and DSA were retrospectively enrolled. The reconstructed resolution of CS TOF-MRA was 0.4 × 0.4 × 0.4 mm3. The scan time was 5 min and 2 s. The image quality of CS TOF-MRA was independently ranked by two neuroradiologists in 1031 arterial segments. The luminal stenosis grades on CS TOF-MRA and DSA were analyzed in 61 arterial segments and were compared using the Wilcoxon signed-rank test. The ability of CS TOF-MRA to predict moderate to severe stenosis or occlusion was analyzed.Results: The image quality of most arterial segments (95.2%) on CS TOF-MRA was excellent. Arterial segments with low image quality were mainly the V3-4 segments of the vertebral artery. The majority of arterial stenoses (62.3%) were located in the cervical internal carotid artery. The luminal stenosis grades of CS TOF-MRA were concordant with that of DSA in 50 of 61 segments (p = 0.366). CS TOF-MRA had a sensitivity of 84.4% and a specificity of 88.5% for predicting moderate to severe stenosis. For detecting occlusion lesions, it had a sensitivity of 100% and a specificity of 94.1%.Conclusion: CS TOF-MRA provides adequate image quality within a reasonable acquisition time and is a reliable tool for diagnosing head and neck arterial steno-occlusive disease.Key Points: • CS TOF-MRA provides a relatively large coverage (16 cm), high resolution (0.4 × 0.4 × 0.4 mm3) and good image quality of head and neck arteries within 5 min and 2 s. • The diagnostic accuracy of CS TOF-MRA in the assessment of moderate to severe stenosis and occlusion was comparable with that of DSA. • Arterial segments with low image quality were mainly the V3 and V4 segments of the vertebral artery.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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