Development of an algorithm for automatic classification of right ventricle deformation patterns in arrhythmogenic right ventricular cardiomyopathy.
Background: Different disease stages of arrhythmogenic right ventricular cardiomyopathy (ARVC) can be identified by right ventricle (RV) longitudinal deformation (strain) patterns. This requires assessment of the onset of shortening, (systolic) peak strain, and postsystolic index, which is time‐cons...
| Publicado en: | Echocardiography Vol. 37; no. 5; pp. 698 - 706 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
May2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143431715&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143431715 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: May2020 vid: 37 iid: 5 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 143431715 143431715 145841805 143431715 10.1111/echo.14671 143431715 ppf: 698 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Development of an algorithm for automatic classification of right ventricle deformation patterns in arrhythmogenic right ventricular cardiomyopathy. aug: au: Groen, Marijn H. A. Bosman, Laurens P. Teske, Arco J. Mast, Thomas P. Taha, Karim Van Slochteren, Frebus J. Cramer, Maarten J. Doevendans, Pieter A. Es, René affil: Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, University of Utrecht, Utrecht, The Netherlands sug: subj: Ventricular Dysfunction, Right Ultrasonography Arrhythmogenic Right Ventricular Dysplasia Algorithms Instrument Construction Instrument Validation Human Automation, Laboratory Descriptive Statistics Mutation ab: Background: Different disease stages of arrhythmogenic right ventricular cardiomyopathy (ARVC) can be identified by right ventricle (RV) longitudinal deformation (strain) patterns. This requires assessment of the onset of shortening, (systolic) peak strain, and postsystolic index, which is time‐consuming and prone to inter‐ and intra‐observer variability. The aim of this study was to design and validate an algorithm to automatically classify RV deformation patterns. Methods: We developed an algorithm based on specific local characteristics from the strain curves to detect the parameters required for classification. Determination of the onset of shortening by the algorithm was compared to manual determination by an experienced operator in a dataset containing 186 RV strain curves from 26 subjects carrying a pathogenic plakophilin‐2 (PKP2) mutation and 36 healthy subjects. Classification agreement between operator and algorithm was solely based on differences in onset shortening, as the remaining parameters required for classification of RV deformation patterns could be directly obtained from the strain curves. Results: The median difference between the onset of shortening determined by the experienced operator and by the automatic detector was 5.3 ms [inter‐quartile range (IQR) 2.7–8.6 ms]. 96% of the differences were within 1 time frame. Both methods correlated significantly with ρ = 0.97 (P <.001). For 26 PKP2 mutation carriers, there was 100% agreement in classification between the algorithm and experienced operator. Conclusion: The determination of the onset of shortening by the experienced operator was comparable to the algorithm. Our computer algorithm seems a promising method for the automatic classification of RV deformation patterns. The algorithm is publicly available at the MathWorks File Exchange. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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