Terminal Ileitis due to Yersinia Infection: An Underdiagnosed Situation.

Endoscopy is currently the gold standard for the diagnosis of inflammatory bowel disease (IBD). The presence of macroscopic lesions along with the microscopic detection of inflammatory infiltration in the terminal ileum often leads the gastroenterologist to the diagnosis of Crohn's disease (CD). How...

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Publicado en:BioMed Research International pp. 1 - 11
Autores principales: Triantafillidis, John K., Thomaidis, Thomas, Papalois, Apostolos
Formato: review Journal Article
Publicado: Wiley-Blackwell 5/27/2020
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
      issn: 23146133
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    pubinfo:
      dt: 5/27/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/1240626
        143456027
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        atl: Terminal Ileitis due to Yersinia Infection: An Underdiagnosed Situation.
      aug:
        au:
          Triantafillidis, John K.
          Thomaidis, Thomas
          Papalois, Apostolos
        affil: Metropolitan General Hospital, Athens, Greece
      sug:
        subj:
          Crohn Disease Etiology
          Yersinia Infections Complications
          Yersinia Infections Diagnosis
          Yersinia Infections Physiopathology
          Antibodies, Bacterial Blood
          Food Microbiology
          Water Microbiology
          Prevalence
          Histological Techniques Methods
          Endoscopy, Gastrointestinal
          Crohn Disease Diagnosis
          Yersinia Infections Epidemiology
      ab: Endoscopy is currently the gold standard for the diagnosis of inflammatory bowel disease (IBD). The presence of macroscopic lesions along with the microscopic detection of inflammatory infiltration in the terminal ileum often leads the gastroenterologist to the diagnosis of Crohn's disease (CD). However, some of these cases could be, in fact, an infection caused by Yersinia spp., accompanied or not with CD, which could be easily diagnosed with the identification of serum antibodies against Yersinia outer protein antigens (YOP antigens). Since Yersiniosis is considered to be an uncommon situation, food and water are not usually checked for the possibility of contamination by Yersinia. Therefore, it is reasonable to assume that the true prevalence of Yersinia infection in patients with terminal ileitis is probably underestimated. In this article, we review the most important data regarding the various aspects of Yersinia infection with special focus on its pathophysiology and diagnosis. We recommend testing for serum antibodies against YOP antigens in all patients with an endoscopic and histological image of terminal ileitis in order to identify Yersiniosis in conjunction or not with terminal ileum CD.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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