Automated Cardiovascular Pathology Assessment Using Semantic Segmentation and Ensemble Learning.

Cardiac magnetic resonance imaging provides high spatial resolution, enabling improved extraction of important functional and morphological features for cardiovascular disease staging. Segmentation of ventricular cavities and myocardium in cardiac cine sequencing provides a basis to quantify cardiac...

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Publicado en:Journal of Digital Imaging Vol. 33; no. 3; pp. 607 - 613
Autores principales: Lindsey, Tony, Lee, Jin-Ju
Formato: diagnostic images research tables/charts Journal Article
Publicado: Springer Nature Jun2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2020
      vid: 33
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-019-00197-0
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        atl: Automated Cardiovascular Pathology Assessment Using Semantic Segmentation and Ensemble Learning.
      aug:
        au:
          Lindsey, Tony
          Lee, Jin-Ju
        affil: Intelligent Systems, NASA Ames Research Center, Room 250, M/S N269-2, 94035, Mountain View, CA, USA
      sug:
        subj:
          Cardiovascular Diseases Diagnosis
          Automation
          Magnetic Resonance Imaging Methods
          Image Processing, Computer Assisted Methods
          Machine Learning
          Human
          Neural Networks (Computer)
          Myocardium Pathology
          Heart Ventricle Pathology
          Cardiovascular Diseases Classification
          Academic Medical Centers
          France
      ab: Cardiac magnetic resonance imaging provides high spatial resolution, enabling improved extraction of important functional and morphological features for cardiovascular disease staging. Segmentation of ventricular cavities and myocardium in cardiac cine sequencing provides a basis to quantify cardiac measures such as ejection fraction. A method is presented that curtails the expense and observer bias of manual cardiac evaluation by combining semantic segmentation and disease classification into a fully automatic processing pipeline. The initial processing element consists of a robust dilated convolutional neural network architecture for voxel-wise segmentation of the myocardium and ventricular cavities. The resulting comprehensive volumetric feature matrix captures diagnostic clinical procedure data and is utilized by the final processing element to model a cardiac pathology classifier. Our approach evaluated anonymized cardiac images from a training data set of 100 patients (4 pathology groups, 1 healthy group, 20 patients per group) examined at the University Hospital of Dijon. The top average Dice index scores achieved were 0.940, 0.886, and 0.849 for structure segmentation of the left ventricle (LV), myocardium, and right ventricle (RV), respectively. A 5-ary pathology classification accuracy of 90% was recorded on an independent test set using the trained model. Performance results demonstrate the potential for advanced machine learning methods to deliver accurate, efficient, and reproducible cardiac pathological assessment.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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