Real-time Malaria Parasite Screening in Thick Blood Smears for Low-Resource Setting.

Malaria is a serious public health problem in many parts of the world. Early diagnosis and prompt effective treatment are required to avoid anemia, organ failure, and malaria-associated deaths. Microscopic analysis of blood samples is the preferred method for diagnosis. However, manual microscopic e...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Digital Imaging Vol. 33; no. 3; pp. 763 - 776
Autores principales: Chibuta, Samson, Acar, Aybar C.
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jun2020
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143476523&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 143476523
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        08971889
        DOQ
      jtl: Journal of Digital Imaging
      issn: 08971889
      maglogo: N
    pubinfo:
      dt: Jun2020
      vid: 33
      iid: 3
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        143476523
        143476523
        143476523
        10.1007/s10278-019-00284-2
        143476523
      ppf: 763
      ppct: 13
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Real-time Malaria Parasite Screening in Thick Blood Smears for Low-Resource Setting.
      aug:
        au:
          Chibuta, Samson
          Acar, Aybar C.
        affil: Health Informatics Department, Middle East Technical University, Ankara, Turkey
      sug:
        subj:
          Malaria Blood
          Parasites Analysis
          Image Processing, Computer Assisted Methods
          Microscopy Methods
          Human
          Costs and Cost Analysis
          Sensitivity and Specificity
          Deep Learning
          Algorithms
      ab: Malaria is a serious public health problem in many parts of the world. Early diagnosis and prompt effective treatment are required to avoid anemia, organ failure, and malaria-associated deaths. Microscopic analysis of blood samples is the preferred method for diagnosis. However, manual microscopic examination is very laborious and requires skilled health personnel of which there is a critical shortage in the developing world such as in sub-Saharan Africa. Critical shortages of trained health personnel and the inability to cope with the workload to examine malaria slides are among the main limitations of malaria microscopy especially in low-resource and high disease burden areas. We present a low-cost alternative and complementary solution for rapid malaria screening for low resource settings to potentially reduce the dependence on manual microscopic examination. We develop an image processing pipeline using a modified YOLOv3 detection algorithm to run in real time on low-cost devices. We test the performance of our solution on two datasets. In the dataset collected using a microscope camera, our model achieved 99.07% accuracy and 97.46% accuracy on the dataset collected using a mobile phone camera. While the mean average precision of our model is on par with human experts at an object level, we are several orders of magnitude faster than human experts as we can detect parasites in images as well as videos in real time.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N