Implementation of a Reference-Scaled Average Bioequivalence Approach for Highly Variable Acetylsalicylic Acid in Fixed-Dose Combination with Clopidogrel Versus Enteric Aspirin in Chinese Subjects Under Fasting Conditions: A Phase 1, Open-Label, Randomized, Crossover Study.

Introduction: Dual antiplatelet therapy, aspirin and a P2Y12 inhibitor, is recommended to prevent thrombotic complications of acute coronary syndrome. Clopidogrel plus acetylsalicylic acid combination is the most commonly used dual antiplatelet therapy recommended by international guidelines and in...

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Publicado en:	Advances in Therapy Vol. 37; no. 6; pp. 2696 - 2710
Autores principales:	Wang, Lu, Di, Yujing, Guo, Tingting, Ming, Jeffrey E., Kong, Fangyuan, Yin, Huiqiu, Zhang, Linlin, Xie, Fang, Yang, Na, Ping, Chuan, Li, Yi, Hou, Jie
Formato:	research randomized controlled trial Journal Article
Publicado:	Springer Nature Jun2020
Acceso en línea:	Ver este registro en EBSCOhost