Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder.
The prevalence of ASD remains relatively stable across the lifespan, necessitating a quantitative understanding of how intervention clinical research is applied across age groups. Here we report a systematic review of treatment studies between 2013 and 2017, enrolling 11,213 subjects with ASD in 218...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 50; no. 6; pp. 2208 - 2217 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143506744&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143506744 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: Jun2020 vid: 50 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 143506744 143506744 143506744 10.1007/s10803-019-03942-0 143506744 ppf: 2208 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder. aug: au: Lewis, Alan S. van Schalkwyk, Gerrit Ian affil: Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, 465 21st Ave. S., MRBIII Room 6140B, 37240, Nashville, TN, USA sug: subj: Autism Spectrum Disorder Therapy Autism Spectrum Disorder Prevention and Control Research Subjects Age Factors Clinical Trials Human Systematic Review PubMed Cochrane Library Child Adolescence Adult Odds Ratio Confidence Intervals Intervention Trials Behavior Therapy Autism Spectrum Disorder Drug Therapy Descriptive Statistics Child: 6-12 years Adolescent: 13-18 years Adult: 19-44 years ab: The prevalence of ASD remains relatively stable across the lifespan, necessitating a quantitative understanding of how intervention clinical research is applied across age groups. Here we report a systematic review of treatment studies between 2013 and 2017, enrolling 11,213 subjects with ASD in 218 studies. Individuals under 18 years old constituted the majority of studies (84%) and subjects (92%). Subjects under 18 years old were more likely to be enrolled in behavioral studies (OR (CI) = 1.34 (1.17–1.54)), and less likely to be enrolled in pharmacological (OR = 0.60 (0.52–0.69)) studies than subjects ≥ 18 years old. Identified disparities in both intervention modalities and outcome measures should serve to guide future research priorities. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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