Multimodal data analysis of epileptic EEG and rs-fMRI via deep learning and edge computing.
Background and Objective: Multimodal data analysis and large-scale computational capability is entering medicine in an accelerative fashion and has begun to influence investigational work in a variety of disciplines. It is also informing us of therapeutic interventions that will come about with such...
| Publicado en: | Artificial Intelligence in Medicine Vol. 104 |
|---|---|
| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Elsevier B.V.
Apr2020
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143617693&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143617693 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09333657 3HY jtl: Artificial Intelligence in Medicine issn: 09333657 maglogo: N pubinfo: dt: Apr2020 vid: 104 pid: 1004 pub: Elsevier B.V. artinfo: ui: 143617693 143617693 NLM32498996 10.1016/j.artmed.2020.101813 NLM32498996 143617693 ppct: 1 formats: tig: atl: Multimodal data analysis of epileptic EEG and rs-fMRI via deep learning and edge computing. aug: au: Hosseini, Mohammad-Parsa Tran, Tuyen X. Pompili, Dario Elisevich, Kost Soltanian-Zadeh, Hamid affil: Department of Electrical and Computer Engineering, Rutgers University, NJ, USA sug: subj: Epilepsy Magnetic Resonance Imaging Brain Electroencephalography Clinical Assessment Tools Scales ab: Background and Objective: Multimodal data analysis and large-scale computational capability is entering medicine in an accelerative fashion and has begun to influence investigational work in a variety of disciplines. It is also informing us of therapeutic interventions that will come about with such development. Epilepsy is a chronic brain disorder in which functional changes may precede structural ones and which may be detectable using existing modalities.Methods: Functional connectivity analysis using electroencephalography (EEG) and resting state-functional magnetic resonance imaging (rs-fMRI) has provided such meaningful input in cases of epilepsy. By leveraging the potential of autonomic edge computing in epilepsy, we develop and deploy both noninvasive and invasive methods for monitoring, evaluation, and regulation of the epileptic brain. First, an autonomic edge computing framework is proposed for the processing of big data as part of a decision support system for surgical candidacy. Second, a multimodal data analysis using independently acquired EEG and rs-fMRI is presented for estimation and prediction of the epileptogenic network. Third, an unsupervised feature extraction model is developed for EEG analysis and seizure prediction based on a Convolutional deep learning (CNN) structure for distinguishing preictal (pre-seizure) state from non-preictal periods by support vector machine (SVM) classifier.Results: Experimental and simulation results from actual patient data validate the effectiveness of the proposed methods.Conclusions: The combination of rs-fMRI and EEG/iEEG can reveal more information about dynamic functional connectivity. However, simultaneous fMRI and EEG data acquisition present challenges. We have proposed system models for leveraging and processing independently acquired fMRI and EEG data. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|