Variability in pathologic interpretation of mandibular invasion.
Objectives/hypothesis: Our objective was to identify the accuracy, sensitivity, and specificity of pathological interpretation of mandibular invasion by oral cavity squamous cell carcinoma (SCC) and compare the sensitivity of detecting mandibular invasion in the erosive versus the infiltrative patte...
| Publicado en: | Laryngoscope Vol. 130; no. 7; pp. 1721 - 1725 |
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| Autores principales: | , , , |
| Formato: | pictorial research Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143745469&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143745469 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0023852X 1GR jtl: Laryngoscope issn: 0023852X maglogo: Y pubinfo: dt: Jul2020 vid: 130 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 143745469 143745469 145783083 NLM31433069 143745469 10.1002/lary.28252 NLM31433069 143745469 ppf: 1721 ppct: 4 formats: tig: atl: Variability in pathologic interpretation of mandibular invasion. aug: au: Namin, Arya W. Zitsch, Robert P. Layfield, Lester J. Zitsch, Robert P 3rd affil: Department of Otolaryngology–Head and Neck Surgery, University of Missouri, Columbia Missouri sug: subj: Mandibular Neoplasms Pathology Carcinoma, Squamous Cell Pathology Mouth Neoplasms Pathology Mandible Pathology Mandibular Neoplasms Surgery Prospective Studies Neoplasm Invasiveness Retrospective Design Mandible Surgery Osteotomy Human ab: Objectives/hypothesis: Our objective was to identify the accuracy, sensitivity, and specificity of pathological interpretation of mandibular invasion by oral cavity squamous cell carcinoma (SCC) and compare the sensitivity of detecting mandibular invasion in the erosive versus the infiltrative patterns of invasion. We also aimed to describe the significance of the terminology the carcinoma "abuts the mandible" in pathologic interpretation of mandibular invasion.Study Design: Retrospective case series.Methods: Mandibulectomy specimens from patients who underwent surgical treatment for oral cavity SCC between January 1, 2005 and December 31, 2015 were retrospectively reviewed by a board-certified anatomic pathologist. The accuracy of pathologic interpretation of mandibular invasion was calculated using the retrospective interpretation of bone invasion as the true interpretation, which was compared to the interpretation on the original pathology report. Incidence of encountering the terminology the carcinoma "abuts the mandible" in the pathology report was calculated.Results: A series of 108 consecutive mandibulectomy specimens were reviewed. Sixty-nine percent (74/108) of cases were interpreted as having mandibular invasion. The accuracy of interpreting mandibular invasion was 84%. The sensitivities for interpretation of mandibular invasion for the erosive and infiltrative patterns of invasion were 77% (30/39) and 91% (32/35), respectively (P = .08). Nine percent (10/108) of pathology reports utilized the terminology the carcinoma "abuts the mandible," and 80% (8/10) of these cases exhibited mandibular invasion.Conclusions: The accuracy of identifying mandibular invasion is 84%, indicating a certain degree of sampling error and variability in interpretation. A precise pathologic definition of mandibular invasion should be applied during the interpretation of these specimens to minimize variability.Level Of Evidence: 4 Laryngoscope, 130:1721-1724, 2020. pubtype: Academic Journal doctype: pictorial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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