Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients.
Background: Non Helicobacter pylori gastric Helicobacters (NHPGHs) are associated with a range of upper gastrointestinal symptoms, histologic and endoscopic findings. For the first time in Iran, we performed a cross-sectional study in order to determine the prevalence of five species of NHPGHs in pa...
| Published in: | BMC Gastroenterology Vol. 20; no. 1; pp. 1 - 8 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Published: |
BioMed Central
6/16/2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=143801504&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 143801504 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 1471230X 1CHO jtl: BMC Gastroenterology issn: 1471230X maglogo: N pubinfo: dt: 6/16/2020 vid: 20 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 143801504 143801504 NLM32546214 10.1186/s12876-020-01331-x NLM32546214 143801504 ppf: 1 ppct: 7 formats: tig: atl: Prevalence of non Helicobacter pylori gastric Helicobacters in Iranian dyspeptic patients. aug: au: Shafaie, Shakiba Kaboosi, Hami Peyravii Ghadikolaii, Fatemeh affil: Department of Microbiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran sug: subj: Helicobacter Infections Microbiology Helicobacter Helicobacter Infections Epidemiology Dyspepsia Microbiology Male Cross Sectional Studies Prevalence Female Peptic Ulcer Microbiology Duodenal Ulcer Microbiology Iran Adult Gastritis Microbiology Adult: 19-44 years Male Female ab: Background: Non Helicobacter pylori gastric Helicobacters (NHPGHs) are associated with a range of upper gastrointestinal symptoms, histologic and endoscopic findings. For the first time in Iran, we performed a cross-sectional study in order to determine the prevalence of five species of NHPGHs in patients presenting with dyspepsia.Methods: The participants were divided into H. pylori-infected and NHPGH-infected groups, based on the rapid urease test, histological analysis of biopsies, and PCR assay of ureA, ureB, and ureAB genes. The study included 428 gastric biopsies form dyspeptic patients, who did not receive any treatment for H. pylori. The samples were collected and sent to the laboratory within two years. H. pylori was identified in 368 samples, which were excluded from the study. Finally, a total of 60 non-H. pylori samples were studied for NHPGH species.Results: The overall frequency of NHPGH species was 10 for H. suis (three duodenal ulcer, three gastritis, and four gastric ulcer samples), 10 for H. felis (one gastritis, three duodenal ulcer, and six gastric ulcer samples), 20 for H. salomonis (four duodenal ulcer, five gastritis, and 11 gastric ulcer samples), 13 for H. heilmannii (three gastritis, five duodenal ulcer, and five gastric ulcer samples), and 7 for H. bizzozeronii (zero gastric ulcer, two duodenal ulcer, and five gastritis samples).Conclusions: Given our evidence about the possibility of involvement of NHPGHs in patients suffering from gastritis and nonexistence of mixed H. pylori infection, bacteriological testing of subjects negative for H. pylori becomes clinically relevant and important. Our findings suggest H. salomonis has the highest rate among the NHPGH species in Iranian dyspeptic patients. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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