Atrophic gastritis and chronic diarrhea due to Helicobacter pylori infection in early infancy: A case report.

Rationale: Helicobacter pylori infection causes atrophic gastritis in childhood, but atrophic gastritis due to H pylori infection is extremely rare in infancy. The relationship between H pylori infection and chronic diarrhea without protein leakage remains controversial.Patient Concerns: An 8-month-...

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Publicado en:Medicine Vol. 98; no. 47; pp. 1 - 8
Autores principales: Toshihiko Kakiuchi, Aiko Nakayama, Ryo Shimoda, Muneaki Matsuo, Kakiuchi, Toshihiko, Nakayama, Aiko, Shimoda, Ryo, Matsuo, Muneaki
Formato: case study Journal Article
Publicado: Lippincott Williams & Wilkins Nov2019
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2019
      vid: 98
      iid: 47
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: Atrophic gastritis and chronic diarrhea due to Helicobacter pylori infection in early infancy: A case report.
      aug:
        au:
          Toshihiko Kakiuchi
          Aiko Nakayama
          Ryo Shimoda
          Muneaki Matsuo
          Kakiuchi, Toshihiko
          Nakayama, Aiko
          Shimoda, Ryo
          Matsuo, Muneaki
        affil: Department of Pediatrics, Faculty of Medicine, Saga University, Saga, Japan
      sug:
        subj:
          Helicobacter Infections Complications
          Helicobacter Pylori
          Gastritis, Atrophic Microbiology
          Diarrhea Microbiology
          Infant
          Male
          Chronic Disease
          Questionnaires
          Infant: 1-23 months
          Male
      ab: Rationale: Helicobacter pylori infection causes atrophic gastritis in childhood, but atrophic gastritis due to H pylori infection is extremely rare in infancy. The relationship between H pylori infection and chronic diarrhea without protein leakage remains controversial.Patient Concerns: An 8-month-old male infant presented to our hospital with severe watery diarrhea, erythema, and failure to thrive from approximately 1 month after birth. Blood, stool, esophagogastroduodenoscopy, total colonoscopy, and H pylori urease analysis results were positive, thereby suggesting atrophic gastritis.Diagnoses: Atrophic gastritis and chronic diarrhea due to H pylori infection.Interventions: We performed H pylori eradication therapy using triple therapy with vonoprazan (6 mg/kg), amoxicillin (300 mg/d), and clarithromycin (120 mg/kg) for 7 days.Outcomes: From approximately 1 week after the H pylori eradication therapy, the frequency of defecation had decreased, stool shape had improved, and body weight had gradually increased.Lessons: H pylori infection can cause atrophic gastritis and chronic diarrhea even in infancy. Early eradication therapy for H pylori infection may be useful for prevention of gastric cancer and improvement in growth disorders.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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