Current Progression: Application of High-Throughput Sequencing Technique in Space Microbiology.

During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of t...

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Publicado en:BioMed Research International pp. 1 - 14
Autores principales: Chen, Yanwu, Wu, Bin, Zhang, Cheng, Fan, Zhiqi, Chen, Ying, Xin, Bingmu, Xie, Qiong
Formato: pictorial review tables/charts Journal Article
Publicado: Wiley-Blackwell 6/22/2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/22/2020
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2020/4094191
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        atl: Current Progression: Application of High-Throughput Sequencing Technique in Space Microbiology.
      aug:
        au:
          Chen, Yanwu
          Wu, Bin
          Zhang, Cheng
          Fan, Zhiqi
          Chen, Ying
          Xin, Bingmu
          Xie, Qiong
        affil: Space Science and Technology Institute (Shenzhen), Shenzhen, China
      sug:
        subj:
          Sequence Analysis Methods
          Environmental Microbiology
          Astronomy
          Environmental Monitoring
          Environmental Pollution
          Space Flight
          Culture Techniques
      ab: During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of the isolation time, harmful bacteria gradually accumulate. Monitoring and controlling microbial pollution in a confined environment system are very important for crew health and the sustainable operation of a space life support system. Culture-based assays have been used traditionally to assess the microbial loads in a spacecraft, and uncultured-based techniques are already under way according to the NASA global exploration roadmap. High-throughput sequencing technology has been used generally to study the communities of the environment and human on the ground and shows its broad prospects applied onboard. We here review the recent application of high-throughput sequencing on space microbiology and analyze its feasibility and potential as an on-orbit detection technology.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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