The 360° circumferential opening of Schlemm's canal in normal individuals detected by enhanced depth imaging optical coherence tomography.

We aimed to observe the opening status and morphological parameters of Schlemm's canal (SC) in normal eyes using enhanced depth imaging optical coherence tomography (EDI-OCT).Consecutive EDI-OCT scans were used to examine the right eye of 20 normal individuals. EDI-OCT was performed clockwise for 8...

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Publicado en:Medicine Vol. 99; no. 7; pp. 1 - 7
Autores principales: Sili Jing, Zhiqi Chen, Wei Chen, Hong Zhang, Junming Wang, Jing, Sili, Chen, Zhiqi, Chen, Wei, Zhang, Hong, Wang, Junming
Formato: Journal Article
Publicado: Lippincott Williams & Wilkins Feb2020
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2020
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      pub: Lippincott Williams & Wilkins
      place: Baltimore, Maryland
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        atl: The 360° circumferential opening of Schlemm's canal in normal individuals detected by enhanced depth imaging optical coherence tomography.
      aug:
        au:
          Sili Jing
          Zhiqi Chen
          Wei Chen
          Hong Zhang
          Junming Wang
          Jing, Sili
          Chen, Zhiqi
          Chen, Wei
          Zhang, Hong
          Wang, Junming
        affil: Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
      sug:
        subj:
          Anterior Eye Segment Anatomy and Histology
          Schlemm's Canal
          Young Adult
          Anterior Eye Segment
          Male
          Research Subjects
          Tomography, Optical Coherence
          Female
          Adult
          Reference Values
          Questionnaires
          Adult: 19-44 years
          Male
          Female
      ab: We aimed to observe the opening status and morphological parameters of Schlemm's canal (SC) in normal eyes using enhanced depth imaging optical coherence tomography (EDI-OCT).Consecutive EDI-OCT scans were used to examine the right eye of 20 normal individuals. EDI-OCT was performed clockwise for 8 regions (at the 12:00, 1:30, 3:00, 4:30, 6:00, 7:30, 9:00 and 10:30 o'clock positions). Image processing and analysis in java software was used to measure the area, perimeter, and diameter of SC. Twenty-one serial scans of each region were evaluated and a total of 168 images were included in the analyses of each eye.The SC was detected in 100.0% of the sections. The distribution of individual measurements of SC was highly variable. The mean values of SC size significantly differed among the different clock-face positions. The mean values of the area, perimeter, and diameter of SC in the 9:00 o'clock position were the lowest, and those at the 7:30 o'clock position were the highest (P < .05). There was no obvious association between intraocular pressure and SC size at any clock position.Although SC tends to open circumferentially in normal individuals, the distribution of individual measurements is highly variable. Morphological manifestation of SC measured by EDI-OCT is a useful way to evaluate the circumferential opening status of SC.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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