Children's heart and COVID-19: Up-to-date evidence in the form of a systematic review.

The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardia...

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Publicado en:European Journal of Pediatrics Vol. 179; no. 7; pp. 1079 - 1088
Autores principales: Sanna, Giulia, Serrau, Gaia, Bassareo, Pier Paolo, Neroni, Paola, Fanos, Vassilios, Marcialis, Maria Antonietta
Formato: research Journal Article
Publicado: Springer Nature Jul2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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        atl: Children's heart and COVID-19: Up-to-date evidence in the form of a systematic review.
      aug:
        au:
          Sanna, Giulia
          Serrau, Gaia
          Bassareo, Pier Paolo
          Neroni, Paola
          Fanos, Vassilios
          Marcialis, Maria Antonietta
        affil: Neonatal Intensive Care Unit, University of Cagliari, Cagliari, Italy
      sug:
        subj:
          Heart Diseases
          Pneumonia, Viral Complications
          COVID-19 Complications
          Prognosis
          Heart Diseases Diagnosis
          Disease Outbreaks
          Heart Diseases Therapy
          COVID-19 Diagnosis
          Child
          Diagnosis, Laboratory
          Pneumonia, Viral Diagnosis
          Risk Factors
          Human
          Child: 6-12 years
      ab: The new coronavirus disease outbreak in 2019 (COVID-19) represents a dramatic challenge for healthcare systems worldwide. As to viral tropism, lungs are not the only COVID-19 target but also the heart may be involved in a not negligible percentage of the infected patients. Myocarditis-related cardiac dysfunction and potentially life-threatening arrhythmias are the main aftermaths. A few studies showed that myocardial injury in adult patients is often linked with a fatal outcome. Conversely, scientific evidence in children is sparse, although several reports were published with the description of a cardiac involvement in COVID-19 paediatric patients. In these young subjects, a background of surgically treated congenital heart disease seems to be a predisposing factor.Conclusion: This systematic review is aimed at summarizing all COVID-19 cases with a cardiac involvement published in paediatric age and trying to explain the underlying mechanisms responsible for COVID-19-related myocardial damage.What is Known:• Coronaviruses proved to be able to jump from animals to humans.• The outbreak of COVID-19 started from China (Dec 2019) and became pandemic.What is New:• Even in childhood, COVID-19 is not without the risk of cardiac involvement.• Myocarditis, heart failure, and arrhythmias are among the possible manifestations.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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