Solid Dispersion Pellets: An Efficient Pharmaceutical Approach to Enrich the Solubility and Dissolution Rate of Deferasirox.

Deferasirox (DFX) is an oral iron-chelating agent and classified into class II of the Biopharmaceutics Classification System. Low bioavailability of the drug due to insufficient solubility in physiological fluids is the main drawback of DFX. The idea of the current study was to explore the potential...

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Publicado en:BioMed Research International pp. 1 - 13
Autores principales: Farmoudeh, Ali, Rezaeiroshan, Anahita, Abbaspour, Mohammadreza, Nokhodchi, Ali, Ebrahimnejad, Pedram
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/24/2020
Acceso en línea:Ver este registro en EBSCOhost