Cooperative parent-mediated therapy for Italian preschool children with autism spectrum disorder: a randomized controlled trial.

Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on social communication skills, but with a wide heterogeneity that requires further research. In this randomized controlled trial (RCT), cooperative...

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Published in:European Child & Adolescent Psychiatry Vol. 29; no. 7; pp. 935 - 947
Main Authors: Valeri, Giovanni, Casula, Laura, Menghini, Deny, Amendola, Filomena Alessandra, Napoli, Eleonora, Pasqualetti, Patrizio, Vicari, Stefano
Format: research tables/charts randomized controlled trial Journal Article
Published: Springer Nature Jul2020
Online Access:View this record in EBSCOhost
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      dt: Jul2020
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-019-01395-5
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        atl: Cooperative parent-mediated therapy for Italian preschool children with autism spectrum disorder: a randomized controlled trial.
      aug:
        au:
          Valeri, Giovanni
          Casula, Laura
          Menghini, Deny
          Amendola, Filomena Alessandra
          Napoli, Eleonora
          Pasqualetti, Patrizio
          Vicari, Stefano
        affil: Department of Neuroscience, IRCCS Children's Hospital Bambino Gesù, Piazza Sant' Onofrio, 4 00165, Rome, Italy
      sug:
        subj:
          Cooperative Behavior
          Parental Behavior
          Autism Spectrum Disorder Therapy
          Treatment Outcomes
          Human
          Randomized Controlled Trials
          Child, Preschool
          Child
          Male
          Female
          Communication Skills Evaluation
          Autism Spectrum Disorder Diagnosis
          Scales
          Severity of Illness
          Affective Disorders Diagnosis
          Self Report
          Caregivers
          Stress, Psychological Evaluation
          Multidisciplinary Care Team
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Male
          Female
      ab: Parent-mediated intervention is widely used for pre-schoolers with autism spectrum disorder (ASD). Previous studies indicate small-to-moderate effects on social communication skills, but with a wide heterogeneity that requires further research. In this randomized controlled trial (RCT), cooperative parent-mediated therapy (CPMT) an individual parent coaching program for young children with ASD was administered to preschool children with ASD. All children received the same low-intensity psychosocial intervention (LPI) delivered in community settings, to evaluate the potential additional benefit of CPMT. Thirty-four participants with ASD (7 females; 27 males; aged 2, 6, 11 years) and their parents were included in the trial. The primary blinded outcome was social communication skills, assessed using the ADOS-G social communication algorithm score (ADOS-G SC). Secondary outcomes included ASD symptom severity, parent-rated language abilities and emotional/behavioral problems, and self-reported caregiver stress. Evaluations were made at baseline and post-treatment (at 6 months) by an independent multidisciplinary team. Results documented that CPMT showed an additional benefit on LPI with significant improvements of the primary blinded outcome, socio-communication skills, and of some secondary outcomes such as ASD symptom severity, emotional problems and parental stress related to parent–child dysfunctional interaction. No additional benefit was found for language abilities. Findings of our RCT show that CPMT provide an additional significant short-term treatment benefit on ASD core symptoms, when compared with active control group receiving only LPI.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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