Association between interatrial block, left atrial fibrosis, and mechanical dyssynchrony: Electrocardiography‐magnetic resonance imaging correlation.
Introduction: Advanced interatrial block (IAB) on a 12‐lead electrocardiogram (ECG) is a predictor of stroke, incident atrial fibrillation (AF), and AF recurrence after catheter ablation. The objective of this study was to determine which features of IAB structural remodeling is associated with left...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 31; no. 7; pp. 1719 - 1726 |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts tracings Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144355852&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144355852 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Jul2020 vid: 31 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 144355852 144355852 144355852 10.1111/jce.14608 144355852 ppf: 1719 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Association between interatrial block, left atrial fibrosis, and mechanical dyssynchrony: Electrocardiography‐magnetic resonance imaging correlation. aug: au: Ciuffo, Luisa Bruña, Vanesa Martínez‐Sellés, Manuel Vasconcellos, Henrique Doria Tao, Susumu Zghaib, Tarek Nazarian, Saman Spragg, David D. Marine, Joseph Berger, Ronald D. Lima, Joao A. C. Calkins, Hugh Bayés‐de‐Luna, Antonio Ashikaga, Hiroshi affil: Division of Internal Medicine, University of New Mexico, Albuquerque New Mexico sug: subj: Heart Block Heart Atrium, Left Fibrosis Ventricular Remodeling Diagnosis Magnetic Resonance Imaging Electrocardiography Human Atrial Fibrillation Therapy Catheter Ablation Middle Age Aged Female Male Descriptive Statistics Stroke Volume Middle Aged: 45-64 years Aged: 65+ years Female Male ab: Introduction: Advanced interatrial block (IAB) on a 12‐lead electrocardiogram (ECG) is a predictor of stroke, incident atrial fibrillation (AF), and AF recurrence after catheter ablation. The objective of this study was to determine which features of IAB structural remodeling is associated with left atrium (LA) magnetic resonance imaging structure and function. Methods/Results: We included 152 consecutive patients (23% nonparoxysmal AF) who underwent preprocedural ECG and cardiac magnetic resonance (CMR) in sinus rhythm before catheter ablation of AF. IAB was defined as P‐wave duration ≥120 ms, and was considered partial if P‐wave was positive and advanced if P‐wave had a biphasic morphology in inferior leads. From cine CMR and late gadolinium enhancement, we derived LA maximum and minimum volume indices, strain, LA fibrosis, and LA dyssynchrony. A total of 77 patients (50.7% paroxysmal) had normal P‐wave, 52 (34.2%) partial IAB, and 23 (15.1%) advanced IAB. Patients with advanced IAB had significantly higher LA minimum volume index (25.7 vs 19.9 mL/m2, P =.010), more LA fibrosis (21.9% vs 13.1%, P =.020), and lower LA maximum strain rate (0.99 vs 1.18, P =.007) than those without. Advanced IAB was independently associated with LA (minimum [P =.032] and fibrosis [P =.009]). P‐wave duration was also independently associated with LA fibrosis (β =.33; P =.049) and LA mechanical dyssynchrony (β = 2.01; P =.007). Conclusion: Advanced IAB is associated with larger LA volumes, lower emptying fraction, and more fibrosis. Longer P‐wave duration is also associated with more LA fibrosis and higher LA mechanical dyssynchrony. pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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