Computer-generated STOPP/START recommendations for hospitalised older adults: evaluation of the relationship between clinical relevance and rate of implementation in the SENATOR trial.

Background findings from a recent qualitative study indicate that the perceived clinical relevance of computer-generated STOPP/START recommendations was a key factor affecting their implementation by physician prescribers caring for hospitalised older adults in the SENATOR trial. Aim to systematical...

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Publicado en:Age & Ageing Vol. 49; no. 4; pp. 615 - 622
Autores principales: Dalton, Kieran, Curtin, Denis, O'Mahony, Denis, Byrne, Stephen
Formato: Artículo
Publicado: Oxford University Press / USA Jul2020
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2020
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      pub: Oxford University Press / USA
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        atl: Computer-generated STOPP/START recommendations for hospitalised older adults: evaluation of the relationship between clinical relevance and rate of implementation in the SENATOR trial.
      aug:
        au:
          Dalton, Kieran
          Curtin, Denis
          O'Mahony, Denis
          Byrne, Stephen
        affil:
          Pharmaceutical Care Research Group , School of Pharmacy, University College Cork, Cork, Ireland
          Department of Medicine , University College Cork, Cork, Ireland
          Geriatric Medicine , Cork University Hospital, Cork, Ireland
      su:
        Elder care
        Hospital care of older people
        Physicians
        Human services programs
        Retrospective studies
        Academic medical centers
        Chi-squared test
        Computer software
        Drug prescribing
        Medical protocols
        Medical records
        Comorbidity
        Physician practice patterns
        Acquisition of data methodology
      sug:
        subj:
          Elder care
          Hospital care of older people
          Physicians
          Human services programs
          Retrospective studies
          Continuing Care Retirement Communities
          Software publishers (except video game publishers)
          Computer and software stores
          Computer, computer peripheral and pre-packaged software merchant wholesalers
          Computer and Computer Peripheral Equipment and Software Merchant Wholesalers
          Offices of physicians
          Offices of Physicians (except Mental Health Specialists)
          Academic medical centers
          Chi-squared test
          Computer software
          Drug prescribing
          Medical protocols
          Medical records
          Comorbidity
          Physician practice patterns
          Acquisition of data methodology
      keyword:
        aged
        hospital
        older people
        pharmacotherapy
        prescribing
        STOPP/START
        aged
        hospital
        older people
        pharmacotherapy
        prescribing
        STOPP/START
      ab: Background findings from a recent qualitative study indicate that the perceived clinical relevance of computer-generated STOPP/START recommendations was a key factor affecting their implementation by physician prescribers caring for hospitalised older adults in the SENATOR trial. Aim to systematically evaluate the clinical relevance of these recommendations and to establish if clinical relevance significantly affected the implementation rate. Methods a pharmacist–physician pair retrospectively reviewed the case records for all SENATOR trial intervention patients at Cork University Hospital and assigned a degree of clinical relevance for each STOPP/START recommendation based on a previously validated six-point scale. The chi-square test was used to quantify the differences in prescriber implementation rates between recommendations of varying clinical relevance, with statistical significance set at P  < 0.05. Results in 204 intervention patients, the SENATOR software produced 925 STOPP/START recommendations. Nearly three quarters of recommendations were judged to be clinically relevant (73.6%); however, nearly half of these were deemed of 'possibly low relevance' (320/681; 47%). Recommendations deemed of higher clinical relevance were significantly more likely to be implemented than those of lower clinical relevance (P  < 0.05). Conclusions a large proportion (61%) of the computer-generated STOPP/START recommendations provided were of potential 'adverse significance', of 'no clinical relevance' or of 'possibly low relevance'. The adjudicated clinical relevance of computer-generated medication recommendations significantly affects their implementation. Meticulous software refinement is required for future interventions of this type to increase the proportion of recommendations that are of high clinical relevance. This should facilitate their implementation, resulting in prescribing optimisation and improved clinical outcomes for multimorbid older adults.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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