Cardiovascular magnetic resonance-derived myocardial strain in asymptomatic heart transplanted patients and its correlation with late gadolinium enhancement.

Objectives: To investigate whether cardiovascular magnetic resonance (CMR)-derived myocardial strains were abnormal in asymptomatic heart transplant (HT) patients with normal left ventricular ejection fraction (LVEF) and to detect the relationship between CMR-derived myocardial strain parameters and...

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Publicado en:European Radiology Vol. 30; no. 8; pp. 4337 - 4347
Autores principales: Shen, Xuehua, Yuan, Yating, Yang, Ming, Wang, Jing, Sun, Wei, Xie, Mingxing, Zhang, Li, Zhou, Xiaoyue, Liang, Bo
Formato: Journal Article
Publicado: Springer Nature Aug2020
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        atl: Cardiovascular magnetic resonance-derived myocardial strain in asymptomatic heart transplanted patients and its correlation with late gadolinium enhancement.
      aug:
        au:
          Shen, Xuehua
          Yuan, Yating
          Yang, Ming
          Wang, Jing
          Sun, Wei
          Xie, Mingxing
          Zhang, Li
          Zhou, Xiaoyue
          Liang, Bo
        affil: Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan, China
      sug:
        subj:
          Ventricular Dysfunction, Right
          Heart Transplantation
          Ventricular Dysfunction, Left
          Heart Ventricle
          Middle Age
          Disease Attributes
          Ventricular Dysfunction, Right Physiopathology
          Adult
          Heart Ventricle Physiopathology
          Reproducibility of Results
          Elements
          Female
          Ventricular Function, Left
          Logic
          Heart
          Myocardium
          Multivariate Analysis
          Stroke Volume
          Male
          Case Control Studies
          Ventricular Dysfunction, Left Physiopathology
          Contrast Media
          Magnetic Resonance Imaging Methods
          Clinical Assessment Tools
          Scales
          Middle Aged: 45-64 years
          Adult: 19-44 years
          Female
          Male
      ab: Objectives: To investigate whether cardiovascular magnetic resonance (CMR)-derived myocardial strains were abnormal in asymptomatic heart transplant (HT) patients with normal left ventricular ejection fraction (LVEF) and to detect the relationship between CMR-derived myocardial strain parameters and late gadolinium enhancement (LGE) in asymptomatic HT patients.Methods: A total of 72 HT patients and 35 healthy volunteers underwent 1.5-T MR scanning. The examination protocol included basic cine imaging and LGE. The deformation registration algorithm (DRA) and feature tracking (FT) software were used for the strain analyses. Myocardial strain measurements included left ventricular global longitudinal strain (LVGLS), LV global circumferential strain (LVGCS), LV global radial strain (LVGRS) and right ventricular longitudinal strain (RVLS).Results: Compared with healthy volunteers, HT patients had significantly decreased DRA- and FT- derived myocardial strain measurements (all p < 0.05). There was a significant correlation and high reproducibility between the DRA- and FT-derived strain parameters. Both CMR-derived LVGLS and LVGRS were significantly related to the presence of LGE, and multivariate logistic regression analyses showed that the LVGLS measurement obtained from both techniques was independently associated with the presence of LGE. The odds ratios (ORs) for DRA- and FT-LVGLS were 1.340 and 1.342, respectively.Conclusions: Asymptomatic HT patients with preserved LVEF exhibited reduced myocardial strain parameters. The CMR-derived LVGLS was independently related to the presence of LGE in HT patients.Key Points: • Reduced myocardial strain parameters were found in asymptomatic heart transplanted (HT) patients with normal left ventricular ejection fraction (LVEF). • The deformation registration algorithm (DRA) and feature tracking (FT)-derived strains in asymptomatic HT patients had high reproducibility. • DRA- and FT-derived LVGLS had an independent relationship with late gadolinium enhancement (LGE) in asymptomatic HT patients.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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