Alcohol use disorders and the brain.
A diagnosis of alcohol use disorder is associated with a higher risk of dementia, but a dose–response relationship between alcohol intake consumption and cognitive impairment remains unclear. Alcohol is associated with a range of effects on the central nervous system at different doses and acts on a...
| Publicado en: | Addiction Vol. 115; no. 8; pp. 1580 - 1590 |
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| Autores principales: | , |
| Formato: | review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144405417&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144405417 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Aug2020 vid: 115 iid: 8 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 144405417 144405417 144405417 10.1111/add.15023 144405417 ppf: 1580 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Alcohol use disorders and the brain. aug: au: Rao, Rahul Topiwala, Anya affil: Institute of Psychiatry, Psychology and Neuroscience, Department of Old Age Psychiatry, London, UK sug: subj: Brain Physiology Central Nervous System Physiology Alcohol-Related Disorders Complications Dementia Risk Factors Dose-Response Relationship Cognition Disorders Risk Factors Wernicke's Encephalopathy Risk Factors Brain Injuries Risk Factors Seizures Risk Factors Stroke Risk Factors Hepatic Encephalopathy Risk Factors Korsakoff Syndrome Risk Factors Alcohol-Related Disorders Epidemiology Alcohol-Related Disorders Therapy Quality of Life Behavior ab: A diagnosis of alcohol use disorder is associated with a higher risk of dementia, but a dose–response relationship between alcohol intake consumption and cognitive impairment remains unclear. Alcohol is associated with a range of effects on the central nervous system at different doses and acts on a number of receptors. Acute disorders include Wernicke's encephalopathy (WE), traumatic brain injury, blackouts, seizures, stroke and hepatic encephalopathy. The most common manifestations of chronic alcohol consumption are Korsakoff's syndrome (KS) and alcohol‐related dementia (ARD). There is limited evidence for benefit from memantine in the treatment of ARD, but stronger evidence for the use of high‐dose parenteral thiamine in the progression of neuropsychiatric symptoms for WE. Accumulating evidence exists for pharmacological treatment in the prevention of hepatic encephalopathy. Rehabilitation of people with ARD may take several years, and requires an approach that addresses physical and psychosocial factors. pubtype: Academic Journal doctype: review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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