Effect of a pharmacist‐led intervention on adherence among patients with a first‐time prescription for a cardiovascular medicine: a randomized controlled trial in Norwegian pharmacies.

Objective: To examine whether a pharmacist‐led intervention improves medication adherence among patients who have filled a first‐time prescription for a cardiovascular medicine. Methods: Design: Unblinded randomized controlled trial. Setting: 67 Norwegian pharmacies, October 2014–June 2015. Particip...

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Publicado en:International Journal of Pharmacy Practice Vol. 28; no. 4; pp. 337 - 346
Autores principales: Hovland, Ragnar, Bremer, Sara, Frigaard, Christine, Henjum, Solveig, Faksvåg, Per Kristian, Sæther, Erik Magnus, Kristiansen, Ivar Sønbø
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Oxford University Press / USA Aug2020
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Effect of a pharmacist‐led intervention on adherence among patients with a first‐time prescription for a cardiovascular medicine: a randomized controlled trial in Norwegian pharmacies.
      aug:
        au:
          Hovland, Ragnar
          Bremer, Sara
          Frigaard, Christine
          Henjum, Solveig
          Faksvåg, Per Kristian
          Sæther, Erik Magnus
          Kristiansen, Ivar Sønbø
        affil: Apokus, National Centre for Development of Pharmacy Practice, Oslo Norway
      sug:
        subj:
          Cardiovascular Diseases Drug Therapy
          Drugs, Prescription Therapeutic Use
          Pharmacists
          Professional Role
          Cardiac Patients Psychosocial Factors
          Medication Compliance
          Human
          Norway
          Randomized Controlled Trials
          Random Assignment
          Adult
          Outcome Assessment
          Scales
          Confidence Intervals
          Adult: 19-44 years
      ab: Objective: To examine whether a pharmacist‐led intervention improves medication adherence among patients who have filled a first‐time prescription for a cardiovascular medicine. Methods: Design: Unblinded randomized controlled trial. Setting: 67 Norwegian pharmacies, October 2014–June 2015. Participants: 1480 adults with a first‐time prescription for a cardiovascular medicine. Intervention: Participants in the intervention group received two consultations with a pharmacist 1–2 and 3–5 weeks after filling the prescription. Participants in the control group received care according to usual practice. Main outcome measure: The primary outcome was self‐reported adherence as measured by the 8‐item Morisky Medication Adherence Scale (MMAS‐8), at 7 and 18 weeks after filling the prescription. Adherence from baseline to week 52 was estimated using data from the Norwegian Prescription Database (NPD). Key Findings: Data from MMAS‐8 showed that 91.3% of the patients in the intervention group were adherent after 7 weeks versus 86.8% in the control group (4.5% difference, 95% CI 0.8–8.2, P = 0.017). The corresponding proportions were 88.7% versus 83.7% after 18 weeks (5.0% difference, 95% CI 0.8–9.2, P = 0.021). NPD data (n = 1294) showed no significant difference in adherence after 52 weeks (95% CI −2.0 to 7.8, P = 0.24). However, adherence among statin users (n = 182) was 66.5% in the intervention group versus 57.4% among new statin users in the general population (n = 1500) (difference 9.1%, 95% CI 1.5–16.0, P = 0.019). Conclusion: The main outcome measure indicates that a short, structured pharmacist‐led intervention may increase medication adherence for patients starting on chronic cardiovascular medication. However, these findings could not be confirmed by the NPD data analysis.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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