Higher anhedonia during withdrawal from initial opioid exposure is protective against subsequent opioid self-administration in rats.

Rationale: Understanding factors contributing to individual differences in vulnerability to opioid addiction is essential for developing more effective preventions and treatments, yet few reliable behavioral predictors of subsequent opioid self-administration have been identified in rodents. Sensiti...

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Detalles Bibliográficos
Publicado en:Psychopharmacology Vol. 237; no. 8; pp. 2279 - 2292
Autores principales: Swain, Yayi, Muelken, Peter, Skansberg, Annika, Lanzdorf, Danielle, Haave, Zachary, LeSage, Mark G., Gewirtz, Jonathan C., Harris, Andrew C.
Formato: Journal Article
Publicado: Springer Nature Aug2020
Acceso en línea:Ver este registro en EBSCOhost