Predictors of Long‐Term Opioid Effectiveness in Patients With Chronic Non‐Cancer Pain Attending Multidisciplinary Pain Treatment Clinics: A Quebec Pain Registry Study.
Objective: This study aimed to identify characteristics of individuals who are most likely to benefit from long‐term opioid therapy in terms of reduction in pain severity and improved mental health–related quality of life (mQoL) without considering potential risks. Methods: This was a retrospective...
| Publicado en: | Pain Practice Vol. 20; no. 6; pp. 588 - 600 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2020
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144544188&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144544188 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15307085 HYN jtl: Pain Practice issn: 15307085 maglogo: Y pubinfo: dt: Jul2020 vid: 20 iid: 6 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 144544188 144544188 144544188 10.1111/papr.12883 144544188 ppf: 588 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Predictors of Long‐Term Opioid Effectiveness in Patients With Chronic Non‐Cancer Pain Attending Multidisciplinary Pain Treatment Clinics: A Quebec Pain Registry Study. aug: au: Kaboré, Jean‐Luc Saïdi, Hichem Dassieu, Lise Choinière, Manon Pagé, M. Gabrielle affil: Department of Pharmacology and Physiology, Faculty of Medicine, Université de Montréal, Montreal Quebec, Canada sug: subj: Pain Management Analgesics, Opioid Therapeutic Use Chronic Pain Drug Therapy Multidisciplinary Care Team Pain Clinics Quebec Mental Health Quality of Life Human Prospective Studies Retrospective Design Quebec Adult Middle Age Male Female Descriptive Statistics Odds Ratio Confidence Intervals Scales Questionnaires Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Objective: This study aimed to identify characteristics of individuals who are most likely to benefit from long‐term opioid therapy in terms of reduction in pain severity and improved mental health–related quality of life (mQoL) without considering potential risks. Methods: This was a retrospective cohort study of 116 patients (age = 51.3 ± 12.5 years, male = 42.2%) enrolled in the Quebec Pain Registry between 2008 and 2011 and who initiated opioid therapy after their first appointment in a multidisciplinary pain clinic and persisted with this treatment for at least 12 months. Clinically significant improvement was defined as a 2‐point decrease on the PEG (pain, enjoyment of life, and general activity) Scale of pain severity (scored from 0 to 10) at 12‐month follow‐up and a 10‐point increase on the Short‐Form‐12 Health Survey version 2 (SF12‐v2) Mental Health‐Related Quality of Life Summary Scale, which corresponds to 1 standard deviation (SD) of the mean in the general population (mean = 50, SD = 10). Results: Clinically significant reduction in pain severity was observed in 26.7% of patients, while improvement in mQoL was reported by 20.2% of patients on long‐term opioid therapy. Older age (odds ratio [OR] = 1.04; 95% confidence interval [CI]: 1.0 to 1.08; P = 0.032) and alcohol or drug problems (OR = 0.26; 95% CI: 0.07 to 0.96; P = 0.044) were weakly associated with pain severity at 12‐month follow‐up. Baseline higher pain severity (OR = 0.62; 95% CI: 0.43 to 0.91; P = 0.014) and baseline higher mQoL (OR = 0.89; 95% CI: 0.83 to 0.95; P = 0.001) were associated with non‐improvement in mQoL. Conclusion: The analysis failed to identify clinically meaningful predictors of opioid therapy effectiveness, making it difficult to inform clinicians about which patients with chronic non‐cancer pain are most likely to benefit from long‐term opioid therapy. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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