Prevalence estimates for pyoderma gangrenosum in the United States: An age- and sex-adjusted population analysis.
Background: The disease burden of pyoderma gangrenosum (PG) is poorly understood.Objective: To determine standardized overall and age-, sex-, and race-specific prevalence estimates for PG among adults in the United States.Methods: Cross-sectional analysis of 1971 patients with PG identified using el...
| Published in: | Journal of the American Academy of Dermatology Vol. 83; no. 2; pp. 425 - 430 |
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| Main Authors: | , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Elsevier B.V.
Aug2020
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=144546119&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 144546119 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01909622 1ZF jtl: Journal of the American Academy of Dermatology issn: 01909622 maglogo: N pubinfo: dt: Aug2020 vid: 83 iid: 2 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 144546119 144546119 NLM31400451 144546119 10.1016/j.jaad.2019.08.001 NLM31400451 144546119 ppf: 425 ppct: 5 formats: tig: atl: Prevalence estimates for pyoderma gangrenosum in the United States: An age- and sex-adjusted population analysis. aug: au: Xu, Amy Balgobind, Amrita Strunk, Andrew Garg, Amit Alloo, Allireza affil: Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York sug: subj: Economic Aspects of Illness Pyoderma Gangrenosum Epidemiology Demography United States Female Sex Factors Risk Factors Middle Age Young Adult Adolescence Prevalence Age Factors Male Aged Cross Sectional Studies Aged, 80 and Over Adult Human Middle Aged: 45-64 years Adolescent: 13-18 years Aged: 65+ years Aged, 80 & over Adult: 19-44 years Female Male ab: Background: The disease burden of pyoderma gangrenosum (PG) is poorly understood.Objective: To determine standardized overall and age-, sex-, and race-specific prevalence estimates for PG among adults in the United States.Methods: Cross-sectional analysis of 1971 patients with PG identified using electronic health records data from a diverse population-based sample of more than 58 million patients.Results: The age- and sex-standardized prevalence of PG among the study population was 0.0058%, or 5.8 PG cases (95% confidence interval [CI], 5.6-6.1) per 100,000 adults. Adjusted prevalence was nearly twice as high among women (7.1 cases [95% CI, 6.7-7.5] per 100,000) than men (4.4 cases [95% CI, 4.0-4.7] per 100,000). Patients between the ages of 70 and 79 years had the highest standardized prevalence (9.8 cases [95% CI, 8.8-10.9] per 100,000), with patients aged ≥50 years representing nearly 70% of all PG cases. Standardized prevalence was similar among white and African American patients. The female-to-male ratio of PG was >1.8 across all age groups.Limitations: Analysis of electronic health records data may result in misclassification bias.Conclusion: PG is a rare disease that most commonly affects women and those aged ≥50 years. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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